Large language models have become capable reasoners and tool users that write and run code and search the literature, which makes automating the research process itself a realistic goal. We present PAPERCLAW, a harnessed multi-agent system that carries a project autonomously, from a field of study to a finished paper. PAPERCLAW curates a domain from a field's live literature, datasets, and code; brainstorms it into an idea with a pre-registered main-result contract; and drives a stoppable hypothesis map through an iterative propose, test, reflect loop that grows only from measured verdicts and halts once the evidence supports the idea, at which point it writes a venue-compliant paper. A full-lifecycle memory keeps each stage in a single living record, so a long run can be paused, inspected, and resumed without losing context. At the centre is an in-cycle research assistant with research tools and skills: it can drive the whole pipeline on its own, while the same interface lets a person step in at any stage, turning a first autonomous draft into a stronger paper through human-in-the-loop refinement. Throughout, PAPERCLAW keeps its output grounded and checkable, citing only references validated against open scholarly indexes and reporting results that genuinely ran. An evaluation with an LLM judge finds that PAPERCLAW produces strong papers both fully autonomously and with human-in-the-loop refinement.
Large language model (LLM) agents are increasingly embedded in scientific workflows for literature analysis, drafting, and review. Existing systems advance autonomous discovery and manuscript generation, but do not resolve the governance problem that arises when ideas, methods, results, and claims propagate through AI-assisted workflows without mandatory human approval or artifact-level traceability. This paper proposes Paper Pilot, a human-in-the-loop expert system for evidence-traceable scientific manuscript generation in applied sciences. It adapts the Collaborative Agent Reasoning Engineering (CARE) methodology to manuscript development through manuscript-owner approval gates, explicit no-pass criteria, claim classification, audit logging, advisory LLM review, and evidence-locked revision control. The framework defines eight approval gates across the idea-to-claim pipeline and distinguishes literature-grounded from artifact-grounded claims, requiring reported numbers and interpretations to remain traceable to approved evidence; its system prompt is openly released for deployment in ChatGPT, Gemini, Claude, or institutional LLM environments. As a first empirical validation, we evaluate the citation-grounding layer with a controlled, mechanically scored benchmark (two commercial LLMs, real arXiv papers, no LLM judge): under coverage pressure ungated drafters fabricated up to 25% of their citations and never flagged an evidence gap, whereas the same models under Paper Pilot's evidence-locked rules produced zero fabricated citations and surfaced the planted gaps as explicit placeholders. Preliminary results for result grounding, revision, and adversarial robustness point the same way; full evaluation is left to future work. Paper Pilot positions LLM-assisted writing as a controlled human-AI decision-support process rather than a fully autonomous authorship pipeline.