Martina Radoynova, Samuel Pantze, Trina De +2cs.CV q-bio.QM
Deep learning computer vision for scientific applications requires collecting and annotating large datasets in a laborious, expensive and error-prone process. Synthetic data generation through 3D modelling and rendering may simplify this process and increase the accuracy of annotations by generating them programmatically. However, minimising the domain gap between real and synthetic images visually is subjective and lacks systematic quantitative guidance. We present GraNatPy, a Python package with metrics to guide improvement of the rendered scene. We show that quantifiable increase in realism, diversity and size of rendered dataset correlates with improved visual perception of the scene and higher zero-shot performance of an object detection model. Furthermore, we demonstrated using photographs of virological plaque assays that gradient similarity affects performance on small object detection, which can be improved by mixing real and synthetic data. Finally, we turn procedural data rendering into an agentic skill (SynthClaw) to automate the procedural parameter optimisation.
Vision-language models (VLMs) and agentic AI have shown strong performance on semantic visual tasks, but it remains unclear whether they can handle the physics and inverse problems that underlie computational imaging. We present ImagingBench, a benchmark of 20 computational imaging tasks spanning five categories: ray and wave optics, image signal processing, inverse reconstruction, computational sensing, and calibration. ImagingBench evaluates three complementary settings: Expert, fixed expert-guided inverse reconstruction; Planner, planner-guided inverse reconstruction; and Forward, forward-system simulation for consistency checking. We benchmark leading proprietary and open-source image-centric multimodal systems, including Gemini, GPT, and Qwen, and compare them with representative task-specific non-agentic baselines. Across tasks, agentic models remain consistently weaker than specialized methods, especially on computational sensing problems such as lensless imaging, event-based reconstruction, time-of-flight imaging, and holography. Planner guidance provides only modest and inconsistent gains over the fixed-prompt Expert baseline. Although the models often generate visually plausible outputs, their reference-based fidelity remains poor, revealing a substantial gap between semantic visual competence and physically grounded imaging performance. ImagingBench provides a unified testbed for measuring this gap and tracking progress in agentic AI for computational imaging.