In object detection, the number of instances is typically used to determine whether a dataset exhibits a long-tailed distribution, implicitly assuming that the model will perform poorly on categories with fewer instances. This assumption has led to extensive research on category bias in datasets with imbalanced instance numbers. However, even in datasets where instance numbers are relatively balanced, models still exhibit category bias, indicating that instance count alone cannot explain this phenomenon. In this work, we first introduce the concept and measurement of information density. We then observe a significant negative correlation between a category's information density and its accuracy, and we investigate how the training process impacts this relationship. Empirical studies suggest that information density imbalance may be a potential source of category bias. To preliminarily validate the potential of information density, we made simple improvements to three advanced object detection loss functions using this concept. Experiments on the Pascal VOC, COCO-LT, and LVIS datasets demonstrate that information density can significantly reduce model bias while effectively enhancing the overall performance of existing loss functions. This study provides a new perspective for understanding the generalized bias phenomenon in object detection models and offers new tools for designing fairer loss functions and training strategies.
Instance-sensitive losses for semantic segmentation such as blob loss and CC loss were designed to address instance imbalance, ensuring small lesions generate the same gradient as large ones, but operate only on single-class segmentation. In multi-class settings, class imbalance poses an additional problem: rare classes with few instances receive a disproportionately small share of the training signal. We show that extending instance-sensitive losses to multi-class segmentation via a one-vs-rest class decomposition repurposes them to also address class imbalance, as uniform averaging over classes ensures each class contributes equally regardless of frequency. We further show that inverse-size weighting, which destabilizes training when applied globally due to weight imbalances across rare and common classes, becomes effective when integrated within the per-component loss, confining the reweighting to each component's spatial context. On the BraTS-METS 2025 dataset (260 test cases), multi-class CC loss improves foreground Dice (0.64 +/- 0.26 vs. 0.59 +/- 0.27 baseline) and rare-class Dice, while maintaining Panoptic Quality at DSC threshold 0.5. Multi-class blob loss achieves the best Panoptic Quality at threshold 0.5 (0.40 +/- 0.24 vs. 0.38 +/- 0.25 baseline) and recognition quality (0.53 +/- 0.29 vs. 0.49 +/- 0.30). Integrating inverse-size weighting within the per-component loss increases rare-class Dice to 0.44 +/- 0.36 at the cost of reduced detection quality.