Lin Li, Chaochao Zhou, Benjamin Aubert +2eess.IV cs.CV cs.LG math.NA physics.comp-ph
Accurate geometric calibration is essential for fluoroscopy-guided spinal imaging, digitally reconstructed radiograph (DRR) generation, and 2D--3D vertebral registration. Although calibration quality is typically evaluated using reconstruction-based metrics such as reprojection error, its influence on projection-domain consistency remains poorly understood. This study presents a synthetic framework for evaluating how intrinsic calibration perturbations affect vertebral fluoroscopic projections and downstream registration performance. CT-derived vertebral models and controlled cone-beam imaging geometry were used to generate DRRs with both ground-truth and perturbed intrinsic calibration parameters while maintaining identical anatomy and acquisition pose. Projection-domain changes were quantified using anatomical landmark displacement, contour distance, silhouette overlap, image similarity, and landmark-based 2D--3D registration accuracy in anterior--posterior (AP) and lateral (LAT) views. Results show that even small intrinsic calibration perturbations produce measurable changes in vertebral projection geometry, contour morphology, landmark localization, and DRR appearance. Sensitivity is strongly view dependent, with LAT projections exhibiting substantially greater deformation and anatomical displacement than AP projections. These projection inconsistencies also degrade downstream 2D--3D registration, particularly rotational alignment accuracy. The findings demonstrate that projection-domain consistency complements conventional reconstruction-based calibration metrics and provides a practical framework for assessing calibration robustness. This approach may improve the reliability of DRR generation and fluoroscopy-guided vertebral registration in image-guided spinal applications.
Ultrasound (US) is widely used for surgical navigation, yet real-time registration between intraoperative 2D slices and preoperative 3D volumes remains challenging due to partial observability, speckle noise, and the action-dependent US acquisition. Existing methods are one-shot or short-horizon, making it hard for them to gather evidence over time or capture how surgeons adjust probe motion based on on-screen feedback. We propose DreamReg, a belief-driven world-model framework that formulates 2D-3D registration as belief updating over rigid transformations. DreamReg maintains a latent belief state that summarizes past observations and poses information, and continuously refines the transformation through learned dynamics as new slices arrive. During training, DreamReg is exposed to probe-motion trajectories that mimic clinical scanning behavior and learns to update its belief by conditioning pose refinement on the current US observation. During inference, DreamReg refines registration via internal imagination: it rolls out the learned world model to simulate candidate probe motions and their predicted observations, and integrates these imagined outcomes to converge to an accurate rigid transformation. Experiments on CAMUS and u-RegPro datasets demonstrate improved robustness and competitive registration accuracy for real-time guidance compared with state-of-the-art methods.