DobicVLM: Aligning Chest X-Ray Report Generation with Clinically-Grounded Programmatic Rewards via Group Relative Policy Optimization

Medical imaging is a cornerstone of diagnostics, yet automated chest X-ray report generation struggles with structural adherence, anatomical completeness, and semantic faithfulness. We introduce DobicVLM, a vision-language model combining supervised fine-tuning on MedGemma-4B with Group Relative Policy Optimization (GRPO) and clinically-grounded programmatic rewards. Our approach uses interpretable, rule-based reward components; structural verification, anatomical checklist, semantic similarity, and length constraints to enforce clinical standards without neural reward models. Trained on 1,000 de-identified image-report pairs from a private clinical dataset (with ethics approval and compliance to local regulations), DobicVLM is evaluated via blinded expert review on 69 held-out cases. DobicVLM outperforms Gemini 2.5 Flash across the majority of criteria, achieving the highest impression accuracy (27.2%) and medical terminology (86.5%) compared to both Gemini 2.5 Flash and MedGemma 4B baselines, with minor trade-offs in completeness and referrals. This demonstrates GRPO's value for transparent alignment in resource-limited settings. Keywords: Vision-Language Models, Radiology Report Generation, Reinforcement Learning, Medical AI, GRPO

REVA-PO: Stabilizing Reinforcement Learning for Chest X-ray Report Generation

Automated chest X-ray report generation has recently benefited from reinforcement learning (RL) and large language models. However, RL training often suffers from instability or limited exploration due to fixed Kullback-Leibler (KL) regularization and a static reference policy that accumulates KL pressure over time. We propose Response-Weighted and Validation-Anchored Policy Optimization (REVA-PO), a RL framework that stabilizes long-term training via Response-Weighted Regularization (RER) and Validation-Anchored Policy Reset (VAPR). RER dynamically adjusts per-response KL weights based on advantage and reference-policy entropy, relaxing constraints for high-quality responses while tightening them for low-quality ones. Complementarily, VAPR periodically synchronizes the reference and current policies to the best validation checkpoint, resetting accumulated regularization pressure to expand the viable exploration space. To ensure a robust starting point, we employ a three-stage pipeline consisting of warm-up training, classifier-guided supervised fine-tuning, and RL. Extensive evaluations on MIMIC-CXR and IU-Xray demonstrate that REVA-PO sets new state-of-the-art benchmarks in both linguistic quality and clinical accuracy. Notably, BLEU-4 improves by 5.1% on MIMIC-CXR and 3.6% on IU-Xray, while CheXpert F1 and RadGraph F1 scores increase by 4.5% and 12.8%, respectively, over prior leading methods. The code is publicly available at https://github.com/LiGuo12/REVA_PO/.

GTA-Net: Cooperative Game Theory for Vision-Language Alignment in Chest X-Ray Report Generation

Automated chest X-ray report generation requires precise cross-modal grounding to ensure clinically reliable descriptions. However, existing vision-language models rely on implicit attention mechanisms that fail to enforce explicit region-word correspondence and disease-level consistency. We propose Game-Theoretic Alignment Network (GTA-Net), a vision-language framework that formulates report generation as a cooperative game-theoretic alignment problem. The model introduces a BinaryGameAligner that models interactions between image regions and text tokens using similarity-based payoff matrices with Shapley-inspired importance weighting. To enforce clinical semantics, we further develop a Disease-Aware Ternary Aligner, which captures joint interactions among images, reports, and structured disease concepts. GTA-Net combines a Swin-based visual encoder with a LoRA-adapted large language model and is trained with a unified objective for generation and alignment. Experiments on CheXpertPlus and IU-XRay demonstrate state-of-the-art performance across standard generation metrics and improved clinical consistency, highlighting the effectiveness of explicit game-theoretic alignment for medical vision-language generation.