Malaria remains a significant global health burden, necessitating continuous research efforts to understand its complex molecular mechanisms, epidemiology, and potential therapeutic interventions. Extracting essential biomedical information from the vast and constantly growing malaria literature is a challenging task that demands innovative approaches. Recently, pre-trained language models have revolutionized natural language processing tasks, demonstrating remarkable capabilities in various domains. This paper proposes a fine-tuned pre-trained biomedical language model for biomedical information extraction from scientific literature on malaria disease. The proposed methodology selects and preprocesses a large corpus of scientific articles on malaria, and then annotates them with entities of clinical significance. It then leverages BioBERT, a state-of-the-art pre-trained language model, to encode the textual data into context-aware representations. We fine-tune the model using domain-specific annotations and supervised learning to enhance its ability to extract relevant biomedical named entities. Extensive experiments and comparisons with different encoding and machine learning algorithms show that the proposed approach significantly outperforms them in precision, recall, and accuracy. We also publish our human-labeled dataset for entity and relation extraction to enable other health informatics researchers to train advanced models for malaria information extraction.
Breast cancer recurrence, a leading cause of long-term mortality among survivors, requires timely and accurate risk assessment to guide follow-up care and treatment planning. Traditional predictive models, often limited to either structured or unstructured data alone, struggle to capture the full clinical context. This study examines the impact of integrating multi-modal clinical data, including treatment records, pathology reports, and clinician notes, on recurrence prediction. By integrating a rule-based regular expression extraction mechanism with a rigorous precedence-based conflict reconciliation strategy, our approach effectively recovers definitive tumor characteristics from free-text pathology narratives to augment structured records. We also benchmark performance against commonly used feature sets from prior breast cancer studies to assess the added value of multi-modal integration. Single-source and multi-modal inputs are evaluated across a range of machine learning models. Results show that multi-modal integration consistently improves predictive accuracy compared to single-modal methods.