Investigating the Ability of Large Language Models to Analyze Recipes for Diabetes

Several studies have evaluated the ability of Large Language Models (LLMs) for meal planning, yielding positive outcomes. These models can process natural language inputs and leverage learned knowledge from their pretraining to generate meal plans. In this work, we investigate the ability of LLMs to analyze the suitability of given recipes for diabetes. The primary challenge for LLMs is to retrieve relevant dietary guidelines for diabetes, decompose recipes into ingredients and cooking methods, and apply these guidelines to determine the recipe's suitability. To study these challenges, we employ three kinds of prompts namely, (i) Direct Query Prompt (ii) Context-Guided Prompt, and (iii) Exemplary Context Prompt that incorporate different levels of diabetes dietary guidelines from medical sources. We introduce a benchmark dataset curated for this investigation consisting of 7607 recipes that include 3807 recipes suitable for diabetes and 3800 recipes not suitable for diabetes. Our results demonstrate that most LLMs are cautious in predicting recipes as suitable to prevent detrimental outcomes. Further, the models that can reason using the dietary guidelines performed better in predicting the suitability of recipes for diabetes. Overall, Mistral-7B and Llama 70B showed superior performance to their counterparts.

GlucoFM-Bench: Benchmarking Time-Series Foundation Models for Blood Glucose Forecasting

Blood glucose forecasting models are foundational for modern diabetes management systems, as reliable short-term predictions can enable proactive interventions, support automated insulin delivery, and reduce the risk of hypo- and hyperglycemic events. From a modeling perspective, glucose forecasting poses unique challenges due to heterogeneous physiological dynamics across diabetes populations. Traditional machine learning and deep learning models have been extensively evaluated for glucose prediction, yet recent time-series foundation models (TSFMs) remain much less studied in this setting. To bridge this gap, we present GlucoFM-Bench, a comprehensive benchmark evaluating state-of-the-art TSFMs alongside supervised deep learning models for blood glucose forecasting. We assess eight representative architectures, including pre-trained TSFMs, time-series large language models, and task-specific deep learning models, across 15 publicly available diabetes-relevant datasets comprising 1,117 individuals with type 1 diabetes, type 2 diabetes, prediabetes, and no diabetes. Models are evaluated under zero-shot, few-shot, and full-shot protocols, with systematic variation in context length and prediction horizon. Across datasets, pre-trained TSFMs, especially Chronos-2 and TimesFM, show strong zero-shot and few-shot transfer, with the best zero-shot model performing within 5% of the best full-shot supervised model. Yet, when task-specific data are abundant, a lightweight LSTM remains strongest, outperforming TSFMs by 4--21% under full-shot training. Stratified analyses reveal persistent challenges in T1D cohorts and hypo-/hyperglycemic ranges, highlighting the need for evaluation beyond aggregate error metrics. Together, GlucoFM-Bench provides a standardized and reproducible foundation for evaluating, comparing, and improving foundation models for blood glucose forecasting.

An empirical evaluation of the risks of AI model updates using clinical data: stability, arbitrariness, and fairness

Artificial Intelligence and Machine Learning (AI/ML) models used in clinical settings are increasingly deployed to support clinical decision-making. However, when training data become stale due to changes in demographics, environment, or patient behaviors, model performance can degrade substantially. While updating models with new training data is necessary, such updates may also introduce new risks. We evaluated the proposed monitoring framework on four publicly available U.S.-based Type 1 Diabetes datasets containing high-resolution continuous glucose monitoring (CGM) data, comprising approximately 11,300 weekly observations from 496 participants under 20 years of age. All datasets included structured sociodemographic information. Using the prediction of severe hyperglycemia events in children with type 1 diabetes as a case study, we examine how different model update strategies can adversely affect model stability (e.g., by causing predictions to "flip" for a large number of cases after an update), increase arbitrariness in predictions, or worsen accuracy equity and the balance of error rates across subpopulations. We propose multiple dimensions for continuous monitoring to detect these issues and argue that such monitoring is essential for the development of trustworthy clinical decision support systems.