Robust Lightweight Deep Learning Models for Oral Cancer Screening

Oral cancer is a leading cause of mortality in low-to-middle-income countries, where a shortage of specialists delays diagnosis. While point-of-care screening via smartphones offers a scalable solution, developing robust AI for resource-constrained settings poses significant challenges, including class imbalance in training data, variable data quality, and computational constraints on edge devices. In this paper, we present the optimisation of lightweight deep learning models for smartphone-based oral cancer screening. Using a diverse, multi-centre retrospective dataset of approximately 30,000 images acquired over a decade, we systematically evaluate state-of-the-art convolutional, transformer, and hybrid architectures. Through rigorous pipeline ablation, we demonstrate that directly optimising hybrid architectures for the edge strictly outperforms computationally heavy paradigms, such as large models or knowledge distillation. Furthermore, interpretability analysis and simulated noise-stress tests revealed that the system anchors on clinical features and remains robust to unstructured sensor noise, despite vulnerabilities to impulse bit errors. In the held-out test set, our optimised MobileViTv2 models achieved an average sensitivity of 83.2 $\pm$ 1.5% and an average specificity of 86.0 $\pm$ 0.8%, with the best model exhibiting 87.4% sensitivity, 86.5% specificity, and a critical negative predictive value of 97.2% with reference to specialist labels. These results confirm that with targeted architectural selection and streamlined optimisation, interpretable and robust lightweight AI models exhibit high potential for edge deployment to enable automated triage in primary care settings.

Sterilizable Scene Graph Generation for Operating Rooms

Scene graph generation from surgical video enables a holistic and structured understanding of surgical scenes by modeling objects and their semantic relationships. Despite recent advances, state-of-the-art approaches rely on large, parameter-heavy deep learning models that are impractical for deployment in the operating room (OR) due to hardware footprint, hygiene constraints, latency, and data privacy concerns. To the best of our knowledge, this is the first scene graph generation method built on NCAs and the first NCA framework capable of learning structured representations. We introduce SG-NCA, a lightweight scene graph generation framework based on Neural Cellular Automata (NCA), designed for inference in fanless devices critical for OR hygiene protocols. SG-NCA is the first scene graph generation combining NCA-based multiclass segmentation for efficient object detection and feature extraction with a lightweight relation predictor. We evaluate SG-NCA on videos of cataract surgery and cholecystectomy, demonstrating performance comparable to established baselines while requiring 55x fewer parameters. We showcase deployment on fanless edge devices better suited for the OR and demonstrate downstream applications such as surgical video captioning, highlighting SG-NCA's potential for affordable, privacy-preserving, and OR-ready intraoperative scene understanding.

RAG-HAR+: Towards Cost-Efficient LLM-Based Human Activity Recognition for Edge Deployment

Human Activity Recognition (HAR) from wearable sensors supports applications in healthcare, rehabilitation, fitness tracking, and smart environments. Yet, existing deep learning approaches require dataset-specific training, large labeled corpora, and repeated adaptation to new sensor settings or activity taxonomies. Retrieval-Augmented Generation for Human Activity Recognition (RAG-HAR) addresses this by framing HAR as a training-free, retrieval-augmented task, in which statistical descriptions of sensor windows are used to retrieve similar labeled examples that guide LLM-based classification. We introduce RAG-HAR+, a retrieval-first and cost-optimized extension that strengthens retrieval while reducing dependence on LLM-based inference. RAG-HAR+ uses an offline Retrieval Designer Agent to design dataset-specific feature groups from a diverse pool of motion descriptors, enabling sensor windows to be compared using features better aligned with dataset-specific activity patterns. During inference, RAG-HAR+ uses majority voting over retrieved neighbors for samples with strong retrieval evidence and defers only uncertain cases to an LLM-based Ambiguity Resolver Agent. Across six HAR benchmarks, RAG-HAR+ maintains competitive or improved performance while reducing LLM usage, token consumption, and inference time. We further extend the RAG-HAR mobile prototype to demonstrate the practical feasibility of retrieval-first, LLM-assisted HAR in mobile sensing scenarios.

Differentiable Logic Gate Networks for Low-Latency EEG Classification on Edge Devices

Real-time EEG classification on edge devices is bottlenecked by the floating-point arithmetic of conventional neural networks. We investigated Differentiable Logic Gate Networks (Diff-Logic) as a hardware-native alternative that compiles models into pure Boolean circuits executable via bitwise CPU operations. Through rigorous iso-parameter experiments across four EEG datasets spanning two classification tasks, binary dementia detection and 3-class emotion recognition, we compared Diff-Logic against matched-capacity Multi-Layer Perceptron (MLP) and Binarized Neural Network (BNN) baselines at four complexity tiers (50k-500k parameters). On dementia screening, Diff-Logic achieved 80.2% Macro F1, outperforming the MLP baseline by 6.8%. On emotion recognition, the MLP retained a moderate performance advantage but incurred a 2.3$\times$ higher latency and 14$\times$ larger model size when deployed on a power-constrained (7W) Nvidia Jetson Orin Nano CPU (Single-core). Critically, Diff-Logic inference time remained nearly constant across a 10$\times$ increase in model scale, achieving a peak speedup of 2.9$\times$ over MLPs at the largest complexity tier. Our results establish logic-based neural architectures as a practical paradigm for resource-constrained brain-computer interfaces, achieving competitive or superior performance while natively satisfying the latency and memory constraints of portable edge deployment. Code is available on GitHub: https://github.com/Shyamal-Dharia/eeg-difflogic

Multi-Teacher Contrastive Distillation for Edge-Efficient Pathology Foundation Models

Computational pathology foundation models (PFMs) have advanced whole-slide image analysis. However, their size and inference cost hinder local deployment in pathology departments. We propose MuCoDi, a pretraining framework that distills frozen tile embeddings from multiple PFMs into compact edge-oriented encoders. Instead of regressing individual teacher features, MuCoDi trains lightweight MobileOne and RepViT students with a contrastive distillation objective adapted from MoCo v3, where cached Virchow2, UNI2, and H-Optimus-1 embeddings replace momentum-encoder keys. We pretrain students on 14.3M TCGA tiles from only 11.8K WSIs and evaluate frozen encoders on 23 clinically curated downstream classification tasks. RepViT-based MuCoEdge students retain near-teacher performance while reducing model size by orders of magnitude: MuCoEdge-R2.3 and MuCoEdge-R1.5 reach 71.0% external AUROC, within 0.8 percentage points of the best teacher (Virchow2, 71.8%), while MuCoEdge-R2.3 obtains the best external F1 and the second-best AUPRC (51.8% and 53.3%). MuCoEdge-R1.0 reaches 70.9% AUROC with only 6.4M parameters and 1.12 GFLOPs. On a Raspberry Pi 5, sub-million-parameter MobileOne students achieve up to 605-fold single-tile speedup over Virchow2 while retaining 66.5% to 66.9% external AUROC, demonstrating that PFM-quality pathology representations can be moved toward practical edge deployment. Code is available at https://anonymous.4open.science/r/mucodi-6243.

Enabling Real-Time Point-of-Care Ultrasound Segmentation: A GPU-Free Deployment in Resource-Limited Settings

Ultrasound imaging is the most widely adopted medical modality globally due to its low cost and portability, yet artificial intelligence (AI) deployment remains constrained by reliance on GPU-accelerated models, creating a structural paradox where the cost of "intelligence" exceeds that of the imaging device itself. Here, we present the systematic adaptation and extensive evaluation of UltraSeg, an ultra-lightweight architecture originally developed for colonoscopic polyp segmentation, now engineered for point-of-care ultrasound (POCUS) across ten public datasets spanning six anatomical sites (breast, thyroid, kidney, carotid, fetal, and small-animal tumor). We systematically validate both variants in ultrasound domains: UltraSeg-130K (0.13M parameters) achieves 89.7 FPS on single-core CPUs and 34.8 FPS on a refurbished mobile device, while UltraSeg-500K (0.5M parameters) delivers 44.6 FPS on CPU and 16.1 FPS on mobile device. UltraSeg-500K matches or exceeds the Dice performance of the 31M-parameter UNet and approaches 105M-parameter TransUNet in average performance, with superior zero-shot cross-dataset generalization on external validation sets (UDIAT, DDTI). By enabling clinical-grade segmentation without GPU dependency, this work brings AI costs in line with ultrasound accessibility, making advanced diagnostics available in resource-limited settings.

Privacy-Preserving Federated Autoencoder for ECG Anomaly Detection on Edge Devices

Continuous electrocardiography (ECG) monitoring could surface rhythm abnormalities before they escalate into cardiovascular events. However, a deployable system must satisfy three requirements simultaneously: legal-grade privacy (GDPR, HIPAA), real-time inference on constrained edge hardware, and detection quality under non-IID cross-hospital data. We design and evaluate an end-to-end federated system addressing all three for unsupervised 12-lead ECG anomaly detection on PTB-XL dataset, combining three autoencoder families (VanillaAE, ConvAE, VAE), Flower-based federated averaging (FedAvg) across ten simulated hospitals, client-side differentially private SGD (DP-SGD) with a Rényi-DP accountant, and 8-bit integer (INT8) post-training quantization with Raspberry Pi 4 benchmarking. Our main contributions are: an empirical characterization of how these mechanisms compose, practical DP-specific recommendations, and technical and security insights for a clinically sensitive setting. Federated learning matches or exceeds the centralized baseline across all architectures (ConvAE federated area under the ROC curve, AUROC, $0.782$), and an $\varepsilon$ sweep identifies $\varepsilon=4$ as the recommended clinical operating point. INT8 quantization roughly halves model size and cuts Pi 4 latency by up to $44%$ with $<0.12%$ AUROC loss. Crucially, DP and quantization penalties are empirically independent, so practitioners need not trade a strong privacy guarantee for a compact edge footprint. To our knowledge, this is the first system combining federated learning, formal $(\varepsilon,δ)$-DP, unsupervised reconstruction-based detection, and quantized AArch64 deployment.

FADA: Accessible fetal ultrasound interpretation and annotation with a selectively distilled unified vision-language model

A global shortage of trained sonographers limits prenatal ultrasound screening in low- and middle-income countries, where over half of pregnant women receive no skilled sonography. Current deep learning approaches address detection, segmentation, or classification in isolation, each demanding a separate model and expert-specified labels at inference. We present FADA, a unified vision-language model built on Qwen3.5-VL that performs clinical interpretation, classification, detection, and segmentation through a single interpretation-first pipeline without external labels. FADA distills knowledge from four domain-specific foundation models (FetalCLIP, UltraSAM, USF-MAE, UltraFedFM) via offline pre-computed feature caching. Selective distillation, which applies feature alignment only to annotation tasks while interpretation relies on standard fine-tuning, consistently outperforms full distillation across most evaluation axes. The recommended variant, FADA-SKD, achieves 0.8820 mean Dice for segmentation, 0.7671 mAP@0.50 for detection, and 100% structured interpretation compliance. Expert sonographer validation across 237 images confirms clinically acceptable outputs in both autonomous and human-in-the-loop modes, with 73.5% of interpretations scoring perfectly under clinician guidance. The system is trainable on a single consumer GPU and deployable without cloud connectivity. We validate edge deployment by running the compressed 0.8B model on a commodity smartphone (Qualcomm Snapdragon 7 Gen 1, 12 GB RAM) using llama.cpp with GGUF quantization, completing the full 5-phase pipeline in approximately 60 seconds entirely offline. This establishes a practical pathway for integrating AI-assisted fetal assessment with portable ultrasound devices, directly addressing diagnostic access gaps in resource-constrained settings. Code, models, and data are available at https://github.com/mahmoodphd/FADA.

How Much Capacity Does EEG Denoising Need? Ultra-Compact Networks reveal Benchmark Saturation and Metric-Utility Gap

Deep learning EEG denoising architectures have scaled from tens of thousands to tens of millions of parameters, yet no prior study has isolated model capacity as the experimental variable or tested whether reconstruction metrics predict downstream neural-signal utility. We address both gaps by fixing architecture, loss, data split, and training recipe while sweeping only channel width from 1.05K to 40.26K parameters in a minimal depthwise-separable convolutional U-Net. Models were evaluated on the EEGDenoiseNet benchmark, cross-dataset BCI transfer tests, controlled baseline retraining, and downstream motor-imagery classification with five decoder families across all nine BCI Competition IV-2a subjects. Reconstruction performance saturated by 3-6.5K parameters, with post-elbow gains of at most 0.015 correlation coefficient per log10-parameter unit. An 8.46M-parameter baseline retrained under the same pipeline matched the 40.26K compact variant on EOG--a 200x parameter gap yielding no advantage--while a Patch-Transformer control reproduced the same diminishing-return shape. Downstream evaluation exposed a classifier-dependent metric-utility gap: reconstruction-optimized denoising significantly degraded CSP+LDA classification across all nine subjects and three artifact types (best denoised accuracy 0.547 vs. 0.612 noisy baseline; Bonferroni p=0.0488), persisting on naturally recorded trials (Delta=-0.047; BH-FDR q=0.0049). End-to-end neural decoders showed variable or neutral effects. Standard EEG denoising benchmarks are saturated far below current model capacity, and reconstruction metrics do not predict BCI utility. Ultra-compact models at 33-46 KB and 1.27-2.61M FLOPs/segment are practical for edge deployment. These findings argue for capacity-controlled evaluation, harder task-aware benchmarks, and mandatory downstream validation.

LightVesselNet: An Ultra-Lightweight Sub-100K Parameter Network for Retinal Blood Vessel Segmentation

Retinal blood vessel segmentation plays a vital role in the early detection of diabetic retinopathy and glaucoma. While recent deep learning models have achieved great segmentation accuracy, they typically require heavy computational resources, making real-world deployment on edge devices difficult. In this paper, we propose LightVesselNet, an efficient neural network designed for retinal vessel segmentation in a resource-constrained environment. Despite containing only 75K parameters, LightVesselNet performs competitively with much larger models. The network employs a compact encoder decoder architecture enhanced with channel and spatial attention mechanisms, a multi-scale feature aggregation module at the bottleneck, and a subpixel upsampling strategy in the decoder. A dedicated edge residual connection preserves fine vessel detail throughout decoding. Extensive experiments on five publicly available datasets: DRIVE, STARE, CHASEDB1, FIVES, and HRF, yield sensitivity scores of 0.8189, 0.8499, 0.8640, 0.8634, 0.8096, and Dice coefficients of 0.8070, 0.8072, 0.8181, 0.8649, and 0.7686, respectively. LightVesselNet shows improved efficiency (Performance vs Parameter or GFlops) compared to State-of-the-Art models. Cross-dataset evaluation confirms the model's generalisation capability. Overall, LightVesselNet is a strong candidate for deployment in low-resource clinical settings and mobile screening tools.

MambaGaze: Bidirectional Mamba with Explicit Missing Data Modeling for Cognitive Load Assessment from Eye-Gaze Tracking Data

Real-time cognitive load assessment from eye-tracking signals could potentially enable adaptive human-centered-AI such as safety-critical applications such as driver vigilance monitoring or automated flight deck assistance, yet two challenges persist: handling frequent data missingness from blinks and tracking failures, and efficiently modeling long-range temporal dependencies. We propose MambaGaze, a framework that addresses these challenges through 1) XMD encoding, which augments raw features with observation masks and time-deltas to explicitly model data uncertainty, and 2) bidirectional Mamba-2, which captures temporal dependencies with linear computational complexity. Experiments on CLARE and CL-Drive datasets under leave-one-subject-out evaluation show that MambaGaze achieves 76.8% and 73.1% accuracy, respectively, outperforming CNN, Transformer, ResNet, and VGG baselines by 4-12 percentage points. Edge deployment benchmarks on NVIDIA Jetson platforms demonstrate real-time inference at 43-68 FPS with power consumption below 7.5W, confirming feasibility for wearable cognitive load monitoring.

SpineContextResUNet: A Computationally Efficient Residual UNet for Spine CT Segmentation

Automated segmentation of the vertebral column in Computed Tomography (CT) scans is a prerequisite for pathological assessment and surgical planning. However, state-of-the-art methods, particularly those based on Transformers or large-scale ensembles, demand substantial GPU resources, creating a barrier for clinical adoption in resource-constrained environments or on edge devices. To address this, we introduce SpineContextResUNet, a computationally efficient 3D Residual U-Net designed for rapid spinal localization. Our architecture integrates a lightweight Context Block that employs parallel multi-dilated convolutions to capture long-range anatomical dependencies without the high latency of Recurrent Neural Networks (RNNs) or the memory overhead of Self-Attention mechanisms. Extensive validation on two public benchmarks, VerSe2020 and CTSpine1K, demonstrates that our model achieves a Dice score of 88.17% and 88.13% respectively. To evaluate performance under strict hardware constraints, we compared our model against a bottlenecked SwinUNETR scaled to match our ~1.7M hardware footprint. While the constrained Transformer suffers severe performance degradation due to a lack of spatial inductive biases in a limited-data regime, our CNN-based approach successfully maintains high accuracy. Crucially, heavy baselines like TotalSegmentator fail due to memory exhaustion on commodity hardware (Intel Core i5, 8GB RAM), our model performs robust inference, making it a viable solution for point-of-care diagnostics and deployment on edge platforms like the Nvidia Jetson Orin Nano.

Temporal Structure Matters for Efficient Test-Time Adaptation in Wearable Human Activity Recognition

Wearable human activity recognition (WHAR) models often suffer from performance degradation under real-world cross-user distribution shifts. Test-time adaptation (TTA) mitigates this degradation by adapting models online using unlabeled test streams, yet existing methods largely inherit assumptions from vision tasks and underexploit the inherent inter-window temporal structure in WHAR streams. In this paper, we revisit such temporal structure as a feature-conditioned inference signal rather than merely an output-space smoothing prior. We derive the insight that temporal continuity and observation-induced feature deviations provide complementary cues for determining when to preserve or release temporal inertia and where to route prediction refinement during likely transitions. Building upon this insight, we propose SIGHT, a lightweight and backpropagation-free TTA framework for WHAR, enabling real-time edge deployment. SIGHT estimates predictive surprise by comparing the current feature with a prototype-based expected state, and then uses the resulting feature deviation to guide geometry-aware transition routing based on prototype alignment and stream-level marginal habit tracking. Evaluations on real-world datasets confirm that SIGHT outperforms existing TTA baselines while reducing computational and memory costs.