Diffusion models (DMs) have emerged as powerful generative priors for MRI reconstruction with promising results. Yet DM-based methods require extensive iterative refinement, limiting their practical deployment. Consistency models (CMs) provide a compelling alternative, aiming to map out the diffusion trajectory in a single pass, enabling faster generation. In this work, we propose CM-RED, a novel MRI reconstruction method that integrates a pretrained CM into the regularization by denoising (RED) scheme. Our method builds on accelerated proximal gradient RED (RED-APG), and further incorporates controlled noise injection during the update steps to enhance generative diversity and accelerate convergence. Extensive experiments on the fastMRI knee and brain datasets demonstrate that CM-RED achieves high-quality reconstructions across multiple anatomies, contrast weights, acceleration factors, and undersampling patterns, using only 4 network function evaluations (NFEs). The proposed method consistently outperforms existing DM- and CM-based approaches in both quantitative metrics and visual fidelity, and exhibits strong robustness to hyperparameter variations, highlighting CM-RED as an efficient and effective generative framework for accelerated MRI reconstruction. The source code and pretrained models are publicly available at https://github.com/MerveGulle/CM-RED.
Qing Lyu, Jianxu Wang, Mohammad Kawas +2eess.IV cs.CV physics.med-ph
Accelerated magnetic resonance imaging reduces acquisition time, but reconstruction from undersampled k-space can blur diagnostically relevant structures or introduce failures that are not captured by global image metrics. We propose SA-RDM-DC, a Self-Auditing Residual generative Drifting Model with Data Consistency for accelerated knee MRI. The method adapts the newly proposed generative drifting paradigm to accelerated MRI by training a physics-conditioned drift field from the zero-filled reconstruction toward the fully sampled residual correction. It predicts image- and missing-k-space residual corrections, enforces data consistency with acquired k-space, uses frequency-aware and residual drifting supervision to recover fine detail, and produces dense error maps and slice-level risk scores in the same inference pass. We evaluate SA-RDM-DC on multi-coil fastMRI knee data at acceleration factors of 4, 8, and 12, with fastMRI+ pathology annotations for region-level and classifier-based task preservation, and on SKM-TEA for zero-shot and fine-tuned protocol-shift evaluation. Compared with zero-filled reconstruction, UNet-image-SENSE, DC-UNet, Score-Diffusion, ELF-Diff, SENSE-VarNet, and MoDL baselines, SA-RDM-DC achieves the highest SSIM across fastMRI acceleration factors while retaining subsecond per-slice inference and avoiding the long sampling time of iterative diffusion baselines. In pathology-aware analysis, SA-RDM-DC preserves lesion-region structural fidelity and reduces meniscus prediction instability. Its self-auditing scores strongly identify high-error reconstructions on fastMRI and partially transfer as a selective-review signal under SKM-TEA protocol shift. These results support reconstruction evaluation that jointly considers image fidelity, pathology preservation, runtime, and case-specific reliability.