Lumin Chen, Qingyao Tian, Jinpeng Li +5cs.CV cs.AI
Camera localization in bronchoscopy remains a challenging problem due to stringent accuracy requirements, real-time constraints, and limited training data. Compared to natural scenes, the confined anatomical structures demand millimeter-level precision, while intraoperative guidance necessitates low-latency inference. However, existing methods often fail to effectively exploit preoperative geometric priors, limiting their robustness and accuracy. To address these limitations, we propose a unified geometry-aware bronchoscope localization framework (GABL) that effectively fuses preoperative structural priors with paired intraoperative video to estimate 6-DoF camera poses. Specifically, to address visual ambiguity in complex airways, we propose a graph-guided coarse-to-fine localization scheme that effectively leverages structural priors for precise pose estimation. Furthermore, to mitigate pose jitter and bridge the visual-structural gap, we integrate a Transformer-based tracking model with a novel RGB-depth matching objective, jointly enforcing spatio-temporal and geometric consistency. Extensive experiments demonstrate that our method yields remarkable reductions of 8.37% and 31.76% in translation and rotation errors over the prior state-of-the-art, alongside 4 times inference speedup (33.6 FPS) for robust real-time bronchoscope localization. Project website: https://paulili08.github.io/GABL/.
Accurate pulmonary vessel segmentation remains challenging due to the sparse, tortuous, and multi-scale nature of vascular structures, where small branches are easily lost and topology integrity is difficult to preserve under voxel-wise supervision. Existing deep segmentation models primarily optimize binary masks, lacking explicit geometric constraints, thus struggling to recover continuous tubular morphology and fine vascular connectivity. In this study, we introduce MorVess, a morphology-aware segmentation framework that integrates differentiable geometric priors with large-scale foundation model adaptation to achieve fine-grained vascular parsing. MorVess jointly predicts vessel masks, distance maps, and thickness maps, providing explicit supervision for vascular boundaries, centerline consistency, and smooth diameter transitions. A lightweight 2.5D adapter bridges 3D spatial context and 2D SAM representations, while a global-local fusion block aggregates multi-level semantics and geometric cues for high-fidelity topology reconstruction. Across two challenging pulmonary CT benchmarks, MorVess delivers superior Dice, clDice, and HD95 scores, substantially improving small-vessel recovery and global connectivity. These results demonstrate that embedding geometric intelligence into pretrained vision models offers a principled and scalable pathway toward precise vessel analysis and clinically reliable structural quantification. Our source code is available at https://github.com/MaoFuyou/MorVess.