An Empirical Analysis of Continual Learning for Heterogeneous Medical Visual Question Answering

Deploying medical visual question answering (MedVQA) systems in real-world clinical settings requires models that adapt to new clinical tasks without forgetting previously acquired knowledge. Continual learning (CL) provides a practical framework for this setting. Despite rapid progress in medical vision-language models, the behavior of CL methods when training these models across heterogeneous MedVQA tasks remains underexplored. This work presents a systematic evaluation of CL for MedVQA across diverse clinical objectives, including classification, multi-label classification, detection, cell counting, and report generation. Specifically, we explore (1) the ability of existing CL methods to mitigate catastrophic forgetting; (2) their sensitivity to task ordering, analyzing how different task sequences influence performance retention and forgetting; and (3) the evolution of low-rank adaptation parameters as new tasks are learned, revealing patterns of weight drift under different CL methods. Our findings suggest that existing CL methods struggle to maintain stability-plasticity balance when tasks with different objectives and supervision formats are interleaved. Code and full experimental setup will be publicly available.

LoRA-Tuned Large Language Models for Dementia Detection via Multi-View Speech-Derived Features

Early detection of dementia enables timely intervention, and reflecting cognitive impairment, spontaneous speech offers a non-invasive screening modality. Conventional approaches often focus on a single representational dimension -- such as acoustic descriptors, pause modeling, automatic speech recognition (ASR) transcripts, or multimodal fusion -- limiting integrative reasoning across heterogeneous cognitive symptoms. We propose a low-rank adaptation (LoRA)-tuned large language model (LLM) that performs structured multi-view reasoning over four complementary speech-derived signals: ASR transcripts with pause markers, discourse-level topic cues, temporal fluency statistics, and phonological sequences. These cues are encoded within a unified prompt, enabling a single LLM to learn a coherent decision function without modality-specific encoders or late-stage fusion. On ADReSSo, our best model achieves an F1-score of 90.14%, and ablation confirms the complementary contribution of each view.

Fine-tuning a multimodal large language model for clinician-grade autism behavioral scoring from short home videos

Autism spectrum disorder (ASD) affects 1 in 31 US children, yet median age at diagnosis exceeds four years. Artificial intelligence pipelines that provide quantified diagnosis using easy to access observational data (e.g., home videos) could help with earlier diagnosis, and timely delivery of early treatments. We fine-tuned Gemini 2.5 Pro on 400 clinician-rated home videos with low-rank adaptation, training only on 30 behavioral features previously validated to produce reliable predictions when passed to various ML models. On 99 held-out children (49 ASD, 50 neurotypical), inter-rater reliability with clinicians (per-feature weighted Cohen's kappa) improved by 40% (p<0.001), with 27 of 28 evaluable features improving. As an emergent zero-shot capability, direct ASD diagnosis F1 improved by 53% (p<0.001), matching or exceeding clinician outcomes. Classifier-assisted pipelines using fine-tuned LLM-derived behavioral features matched clinician-scored inputs across all tested pathways and achieved 77% accuracy (95% CI: 68-85%) and an AUC of 86% (95% CI: 78-92%). Fine-tuned multimodal LLMs can serve as scalable behavioral feature extractors for use in autism assessment and diagnosis.