On-Device Multi-Species Malaria Detection with Uncertainty-Calibrated Slide-Level Aggregation

Malaria remains a leading cause of mortality in resource-limited settings, where expert microscopists are scarce. Automated diagnosis based on microscopy images thus has strong potential to improve care delivery. But for an algorithm to deploy, a necessary requirement is that it meet a suite of non-obvious (from a machine learning (ML) perspective) clinical constraints. Therefore, in close consultation with a national health center we developed a malaria diagnosis pipeline which addresses key requirements listed by the health care center but typically ignored in the ML malaria literature. In particular, it includes: (i) stopping criteria (to reduce image acquisition and time-to-result); (ii) human-in-the-loop functionality (for review and accountability); (iii) multi-species discrimination (since treatment varies by species); (iv) thick film detection (standard for microscopy); (v) computationally-efficient uncertainty calculations (to aid clinician review); and (vi) an edge device platform (since internet can be spotty in this catchment area). The mobile system performs all inference on-device using YOLOv13n deployed via TensorFlow Lite. It detects four species and white blood cells from Giemsa-stained thick blood smear images, aggregating per-image detections into slide-level parasitemia with World Health Organization (WHO)-standard quantification. This paper highlights these various clinical constraints and offers methods to address them. Evaluated on 2,739 annotated images across all four species, the system achieves mAP@0.5 of 0.863, per-image parasite count correlation of r = 0.812, slide-level r = 0.951 (soft counting, 10 images/slide), and runs entirely offline with a pipeline time of 10.27 +- 1.65 s per image.

ECGLight: Compute-Light Framework For Paper ECG Digitization and Myocardial Infarction Screening

Electrocardiography (ECG) is one of the most widely used tests for diagnosing cardiovascular disease. Yet several remote clinics still utilize paper ECG printouts for their analysis due to limited connectivity and computational capacity. As a result, vast numbers of physical ECGs obtained in remote areas still remain incapable of being accessed by contemporary artificial-intelligence (AI)-based decision support as they require high computational resources or strong high-speed internet connectivity. This causes several cases where conditions like acute coronary occlusion (ACS) is overlooked and reperfusion therapy delayed. Although prior work has tackled digitization and diagnosis separately, and utilized advanced AI models for them, there still remains a lack of a compute-light, on-device framework that reconstructs paper ECGs at high fidelity, while accurately supporting multiple clinically relevant endpoints. We address this need with an end-to-end lightweight on-device digitization-to-diagnosis pipeline that converts a smartphone photo or scan of a paper ECG into a calibrated 12-lead signal and screens for Myocardial Infarction (MI) pathologies, with SHapley Additive exPlanations (SHAP) to support interpretability. Trained and evaluated on 21,799 ECGs from the PTB-XL dataset and further validated on hospital-acquired ECG-Matrix dataset, the complete system runs in <30 s per ECG on CPU-only resources, achieving 95.51% accuracy (F1 = 0.9519) for MI detection on PTB-XL and 88.89% accuracy (F1 = 0.8862) for OMI detection on ECG-Matrix. This work showcases that legacy paper records can be reliably democratized in any part of the world, providing a scalable decision support when digital ECG export, connectivity, or high-end compute are unavailable

Towards Whole Hand and Wrist Kinematic Tracking with a Wearable A-Mode Ultrasound Probe

A-mode ultrasound (US) has emerged as a promising modality for hand and wrist motion tracking. Prior works have mainly addressed static gesture classification or regression of a few degrees of freedom (DoFs), typically relying on non-wearable systems and external computing devices, and highlight the need for strategies to ensure robustness to sensor repositioning. In this work, we propose a framework for robust whole-hand and wrist kinematic tracking via wearable A-mode US using the WULPUS platform, tackling the regression of 23 DoFs directly on the probe. First, we introduce a compact (11285 parameters) multi-output convolutional neural network combined with an incremental training strategy, which improves inter-session generalization and reduces mean absolute error by more than 17% compared to a non-incremental approach. Second, we demonstrate, for the first time, the feasibility of end-to-end hand and wrist kinematic tracking entirely on-device. We deploy the model on the WULPUS nRF52832 microcontroller, achieving 0.73 mJ per inference, 29.1 ms latency, and showing the feasibility of full operation (data acquisition, online inference, and BLE streaming of results) within 33 mW, enabling up to 36 hours of continuous use and an 88% reduction in wireless bandwidth compared to raw data transmission.