Medical AI has demonstrated specialist-level diagnostic accuracy, yet these capabilities remain largely inaccessible in resource-constrained rural settings where bandwidth is scarce, compute is limited, and clinical decision-making requires integrating heterogeneous modalities. We introduce a cloud--edge collaborative architecture that addresses these constraints: lightweight, domain-specific models on the edge transform raw medical data into compact structured outputs, while a cloud LLM synthesizes these outputs into clinical summaries. An LLM-based orchestrator dynamically selects diagnostic tools based on patient context, promoting comprehensive modality coverage without processing irrelevant inputs. We evaluate on 20 multimodal clinical cases spanning cardiac, obstetric, trauma, and screening scenarios under three simulated network profiles (500,kbps--5,Mbps). The hybrid system achieves 98--99% diagnostic tool recall with 92--96% precision, matches or exceeds cloud-only baselines on clinical accuracy, and maintains bandwidth-invariant latency (25--35,s) at 4--15x lower token cost. These results highlight the role of architectural design in enabling efficient multimodal integration and improving factual grounding compared to cloud-only approaches under deployment constraints.
Pneumonia remains a leading global cause of morbidity and mortality, particularly in low resource settings where access to imaging, laboratory testing, and specialist care is limited. Clinical assessment relies on heterogeneous evidence, including symptoms, respiratory patterns, and chest imaging, making screening inherently multimodal. However, many existing computational approaches remain unimodal and focus primarily on radiographs. In this work, we present MultiSense-Pneumo, a multimodal framework for pneumonia oriented screening and triage support that integrates structured symptom descriptors, cough audio, spoken language, and chest radiographs. The system combines deterministic symptom triage, LightGBM based acoustic classification, domain adversarial radiograph analysis using ResNet 18, transformer based speech recognition, and an interpretable multimodal fusion operator. Each modality is transformed into a normalized risk signal and aggregated into a unified screening estimate, enabling transparent and modular decision support. MultiSense-Pneumo is designed for real world deployment under modest computational constraints and can operate fully offline on standard laptop class hardware, making it suitable for community health workers, rural clinics, and emergency response settings. Experimental results demonstrate robustness of the radiograph pathway under domain shifts, while highlighting limitations in minority class recall for acoustic signals. MultiSense-Pneumo is intended as a research prototype for screening and triage support rather than a clinically validated diagnostic system.