Background: Depression frequently co-occurs with ADHD and autism spectrum disorder (ASD), but population-level differences in symptom expression between these groups remain underexplored. Objective: We examined whether social media users with ADHD and ASD differ in how they express DSM-5 depressive symptoms in their tweets, and whether differences persist across varying levels of depressive-content filtering. Methods: We analysed 1,282,437 tweets from 792 users (622 ADHD; 170 ASD) with self-reported diagnoses on Twitter. Tweets were pre-filtered for depressive relevance using zero-shot NLI, then classified into nine DSM-5 symptoms using MentalRoBERTa fine-tuned on ReDSM5. Profiles were mean-centered per user. We applied L1-penalised logistic regression with cross-validation to distinguish ADHD from ASD users, complemented by Pearson correlations for symptom co-occurrence, and tested robustness across five filtering thresholds using bootstrapping. Results: MentalRoBERTa achieved macro-F1 of 0.901 on a held-out set, outperforming the original ReDSM5 benchmark. ADHD vs ASD classification yielded stable but modest performance (cross-validated ROC-AUC 0.645-0.653). Cognitive issues, sleep issues, appetite change, and fatigue leaned toward ADHD, while suicidal ideation and anhedonia leaned toward ASD. A largely shared symptom co-occurrence structure emerged between groups; no pair met our criterion for a robust disorder-specific difference. Conclusions: Population-level differences in depression-related language between ADHD and ASD social media users were consistently observed across thresholds, reflecting reproducibility rather than clinical validity. Findings are exploratory and do not establish differing phenomenology at the individual level.
Adolescence is a critical developmental period marked by heightened emotional sensitivity, social stress, and vulnerability to substance use. However, traditional research methods provide limited access to adolescents' authentic experiences, hindering efforts to develop evidence-based prevention and intervention strategies. Social media provides a unique opportunity to observe adolescents' naturally occurring discussions about substance use, offering valuable insights into their opinions, emotions, and lived experiences that can inform early prevention and intervention strategies. In this study, we analyze large-scale Reddit discussions related to substance use among adolescents between 2018 and 2023. Leveraging hour-by-day temporal analysis, sentiment and emotion classification, and transformer-based topic modeling (BERTopic), we examine the interaction between time, emotion, and semantic content in adolescent substance use discourse. Our findings reveal pronounced weekend and late-night peaks in substance-related discussions, a dominance of negative emotions such as sadness and fear, and distinct semantic topics centered on peer relationships, family conflict, emotional distress, and substance-specific experiences. These findings advance our understanding of adolescent substance use in naturalistic online settings and provide empirical evidence to support the development of more timely, targeted, and evidence-based prevention and intervention strategies.
Computational mental health research has predominantly centered on English-speaking populations, leaving Arabic-language discourse comparatively under-examined. We present an exploratory computational study of 8,147 tweets from 607 users classified by a GPT-4.1 personal-disclosure pipeline as likely lived-experience authors in three condition-specific Arabic-language X (formerly Twitter) Communities. We focus on discourse related to borderline personality disorder (BPD), bipolar disorder, and ADHD, and characterize community-associated linguistic patterns using a multi-domain cultural keyword framework. The results suggest that in this corpus, Bipolar tweets contain more religious and medical vocabulary, BPD tweets contain more relational, identity, and emotional-distress vocabulary, and ADHD tweets more often focus on practical symptoms and medication management. We treat these patterns as hypothesis-generating rather than confirmatory because the corpus is imbalanced across conditions, some subcorpora are temporally concentrated, and the keyword framework is an initial operationalization rather than a validated measurement instrument. The paper contributes a reusable LLM-assisted personal-disclosure pipeline and an exploratory cultural keyword framework for Arabic mental health discourse.