Braided Vision Transformer for Stroke Detection in Multi-view Retinal Fundus Imaging

Stroke remains a leading cause of mortality and morbidity worldwide, emphasizing the importance of its accurate and immediate assessment. Retinal fundus imaging has emerged as a promising modality for stroke assessment, as the retina reflects cerebrovascular and neurological risk factors. Contrary to conventional neuroimaging techniques, retinal fundus imaging offers a non-invasive, cost-effective, and portable alternative for rapid screening. This paper explores the feasibility of retinal fundus imaging for stroke and transient ischemic attack (TIA) detection using macula-centric and optic nerve head-centric views captured from both eyes. Our study introduces, to the best of our knowledge, the first vision transformer model for retinal fundus imaging in stroke assessment, offering a novel approach for capturing retinal patterns. Thereby, we propose the Braided Vision Transformer (BViT) model, which extracts representative features from the given multi-view images while simultaneously capturing inter-view relationships across both eyes, enabling a more informative understanding of retinal biomarkers associated with cerebrovascular events. Experiments conducted on our collected Stroke-Data dataset demonstrate that BViT achieves an AUC score of 0.75 for stroke detection, outperforming regular vision transformers.

Deep probabilistic logic programming for diagnostic reasoning from incomplete information: A case study in stroke detection

In medical applications, raw data is frequently associated with significant privacy concerns, lending particular importance to the encoding of summary statistics from the literature. On the other hand, deep learning has become an invaluable tool for assessing symptoms based on visual or auditory sensor data. DeepProbLog allows for an extensible neuro-symbolic approach that accommodates connectionist components to analyse patient images within a transparent and rigorous probabilistic framework, namely probabilistic logic programming under the distribution semantics. Framed as a case study in stroke detection from multimodal data, this contribution explores the pathway from summary statistics available in the literature to a DeepProbLog-based diagnostic system. It suggests a workflow using established maximum entropy techniques to complete available probabilistic information and the probabilistic logic programming system ProbLog 2 to move from the entropy-maximising causal model to a discriminative neuro-symbolic model expressible within DeepProbLog. The relative performance of models derived from less complete data is analysed alongside the potential of the probabilistic inductive logic programming system ProbFOIL 2 for compressing large discriminative models, and the perspectives and implications of using DeepProbLog for diagnostic reasoning are discussed.