Medical Visual Question Answering (Med-VQA) holds significant promise for clinical decision support, yet faces challenges due to limited annotated data and the high computational demands of existing large vision-language models. We propose MedFG-VQA, a lightweight framework that leverages a memory bank to augment DCT-based low-frequency features and employs graph-enhanced cross-attention for effective visual-textual alignment. Specifically, our approach features two key components: Frequency-Memory Fusion (FMF), which enhances low-frequency features by retrieving from a learnable memory bank built on DCT decomposition, and Graph-Aware Cross-Attention (GACA), which aligns visual-textual features via cross-attention and refines them through graph-convolutional aggregation. To address data scarcity, we construct SynMed-VQA, a large-scale synthetic dataset comprising over 2 million question-answer pairs across 9 imaging modalities and 10 major organs, generated with GPT-4o. Extensive experiments on SynMed-VQA and three other standard biomedical VQA benchmarks demonstrate that MedFG-VQA achieves competitive or superior performance compared to much larger models while maintaining significantly lower computational costs, highlighting its efficiency and potential for clinical deployment.
Dermatological practice routinely involves measuring and tracking lesion size, morphology and texture, as critical components of wound or skin cancer screening, monitoring and diagnosis. To accomplish this task, practitioners often image the skin surface with commonly available off-the-shelf camera sensors. This has led to an overwhelming research focus on 2D methods while these objectives naturally benefit from 3D information. In this paper, we demonstrate that dense monocular 3D reconstructions, metric scale measurements and rich surface normal texture estimates are achievable for both dermoscopic and macroscopic cases without the need for additional hardware or multiple captures. We present DermDepth, the first single-view metric scale 3D model for the dermatological domain and D-Synth, the first synthetic dermoscopic dataset with pixel-perfect 3D information. Our experiments show training DermDepth on D-Synth corrects metric scale error from over 16x to under 1.1x for real dermoscopic data, while preserving geometric quality and increasing texture richness. Fine-tuning on a small amount of real clinical samples generalizes our method across three real-world benchmarks spanning the few mm to hundred cm range, diverse skin-tones, chronic wound cases and produces measurements broadly consistent with disease size reported in medical literature. All code, data and models are available at https://github.com/hectorcarrion/dermdepth.
3D reconstruction could improve colonoscopy by estimating mucosal coverage and alerting clinicians to missed regions during screening. However, algorithm development is limited as no current datasets provide both a realistic in vivo appearance and dense, time-resolved 3D ground truth, especially under non-rigid deformation. We present C3VD-DEFCOL, a framework and dataset for evaluating deformable colonoscopy reconstruction with paired geometry and realistic texture. Starting from C3VD/C3VDv2 colon meshes and camera trajectories, we generate controlled deformations of the colon surface, including peristaltic waves and centerline motion, and render per-frame depth, surface normals, optical flow, camera poses, and time-stamped 3D meshes. We then use the rendered geometry, primarily depth, to condition an LTX-2.3-based sim-to-real translation model that produces RGB clips with in vivo-like mucosal color, texture, vasculature, and specular appearance while preserving the underlying 3D scene structure. The resulting dataset contains 110 videos from 11 unique colon mesh geometries, with varying camera trajectories, appearances, and parameterized deformation regimes, including three peristaltic severity levels that serve as controlled evaluation axes. We evaluate the generated videos using appearance realism, geometric consistency, and temporal consistency metrics, and use the paired ground truth to benchmark the downstream task of pose estimation in deformable 3D reconstruction. Our experiments show how pose estimation error increases with increasing deformation severity, providing a controlled stress test that is not possible with existing in vivo datasets. Overall, C3VD-DEFCOL is designed as a reproducible, quantitative evaluation platform for testing deformable 3D reconstruction algorithms, with the goal of reducing the domain gap between synthetic datasets and in vivo colonoscopy.
Guilherme C. Oliveira, Stephanie Fong, Zimu Wang +10cs.CL cs.AI cs.HC
Progress on AI for psychosis-risk assessment is limited by a data-access bottleneck. Real clinical interviews are difficult to share because of privacy, governance, and consent constraints. We present AnchorSIPS, a synthetic dataset of 10K structured psychosis-risk interviews with transcript-grounded measurement targets. Each interview is modeled on Mini-SIPS, a clinician-administered psychosis-risk interview. It captures history, 24 symptom questions, follow-up evidence for items the patient affirms, decisions about delusion-like symptoms (unusual beliefs), hallucination-like symptoms (unusual perceptions), and disorganized communication, exclusion of clear psychotic-level symptoms ("frank psychosis"), and a final attenuated psychosis syndrome (APS) diagnosis, a high-risk state of milder or early psychotic symptoms. The APS diagnosis is not a standalone label. It depends on earlier endorsements, supporting follow-up details, symptom-class decisions, and the frank-psychosis check. Every intermediate decision is anchored to its supporting transcript turns. AnchorSIPS is generated by a plan-then-realize pipeline. A hidden case sheet specifies the patient's clinical state, a deterministic planner fixes the interview structure, and an LLM realizes only the patient utterances under validation and bounded repair. Fixing labels and structure before generation avoids the inter-turn inconsistencies typical of multi-turn LLM dialogue. Across seven LLM baselines, models recover coarse decisions but fail to extract follow-up details or cite supporting transcript turns, so final-label performance overstates interview competence. AnchorSIPS is intended for research on evidence extraction, transcript-grounded measurement, and uncertainty under partial disclosure.