Healthcare workforce scheduling is an NP-hard optimization problem requiring simultaneous satisfaction of labor regulations, coverage requirements, employee preferences and cost objectives. Existing approaches (genetic algorithms, integer programming, constraint programming) model 6-12 constraints at shift-level granularity and cannot guarantee regulatory compliance. They also lack support for multi-role, multi-skill heterogeneity, mandatory break scheduling with midpoint control, acuity-weighted workload equity, sub-shift granularity, inter-week stability, and cross-midnight shifts. This paper presents CP-SAT: a Constraint Programming formulation for multi-role, multi-skill healthcare scheduling. CP-SAT enforces 14 hard constraints guaranteeing zero regulatory violations, while optimizing 15 soft objectives via a unified weighted penalty function. Contributions include a shift-window decomposition enabling break scheduling with centrality control, acuity-weighted workload equity, multi-granularity resolution from 15 minutes to 1 day, inter-week stability, and grid-offset preprocessing mapping cross-midnight shifts into a single scheduling day without solver changes. CP-SAT is evaluated on 18 instances: five synthetic hospital units (10-33 nurses), 10 INRC-II benchmarks (5-80 nurses, up to 8-week horizons) and 3 NRP-23 compatible instances (10-25 nurses) with cross-midnight Night shifts. Results: zero hard-constraint violations across all 18 instances by construction; proven optimality on INRC-II n005w4 (objective 118, gap 0.0%, 104s); feasible schedules scaling to 179,800 variables and 351,425 constraints (80 nurses); service quality improved 50-67% over MOGA; and model size scaling near-linearly at approximately 4,400 variables per employee. The formulation enforces 29 total constraints (14 hard, 15 soft), nearly three times the industry average.
Harshkumar Oza, Aritra Sarkar, Syed Naqi Abbas +4quant-ph cs.AI cs.ET
As quantum computing progresses from proof-of-principle demonstrations toward practical utility, a significant impediment is the need to augment algorithmic feasibility with system-level optimization across heterogeneous hardware and software stacks. Quantum resource estimation (QRE) plays a central role in this transition, yet existing approaches remain largely compilation-heavy or domain-knowledge-guided symbolic annotations, and tightly coupled to long-term fault-tolerant assumptions, limiting their topical applicability. In this work, we introduce AutoQuREO, an Automated framework for full-stack Quantum Resource Estimation and Optimization. AutoQuREO is built around four core novelties: (i) a flexible, user-defined abstraction of the quantum computing stack; (ii) a modular library of reusable stack components enabling rapid full-stack prototyping; (iii) surrogate modeling of layer-wise resources via algorithmic profiling and neuro-symbolic learning; and (iv) integrated multi-objective optimization that embeds QRE directly into deployment pipelines. Together, these design choices enable AutoQuREO to serve as a digital twin for quantum computing stacks, supporting the tractable exploration of complex design spaces. We demonstrate the capabilities of AutoQuREO through representative co-design case studies, including early-fault-tolerant quantum algorithms, small error correction codes, gate decomposition and variational training of parametric quantum circuits. These examples illustrate how AutoQuREO enables systematic discovery of unexploited resource trade-offs that are computationally intractable or abstruse using existing QRE tools. AutoQuREO is positioned as a general-purpose platform for advancing quantum technology readiness.