Vascular computed tomography datasets are commonly annotated only once per scan, yielding the pervasive yet under addressed problem of single mask annotation noise. Existing solutions either require costly multirater fusion or are coupled with network training, preventing explicit auditing of where and why labels fail. We introduce a decoupled framework for single-mask annotation noise detection that leverages cross-sectional patch self-consistency to produce interpretable and auditable noise evidence. Tubular anatomy exhibits strong cross-sectional recurrence: patches extracted orthogonally along vessel centrelines recur in appearance across locations and subjects. Thus, anatomically similar patches should have consistent masks, and disagreement signals unreliable annotation. Our method samples cross-sectional patches, retrieves intensity-equivalent neighbours via scalable vector search, and computes a patch-level noise score from statistical mask disagreement, yielding explicit image-mask evidence for every flagged region. Aggregating scores produces scan-level quality maps for dataset quality assessment or quality-weighted training. Experiments on the coronary CT dataset validate the detected noise for improving training robustness and reveal systematic annotation biases. Specifically, transverse and oblique vessels exhibit 5.1 times higher error rates than axis-aligned structures, with additional correlations to cross-sectional area and intensity. Code is available here.
Automated detection of intracranial aneurysms (IAs) from CT angiography (CTA) is severely hindered by high false-positive rates. Convolutional neural networks (CNNs) rely on local pixel intensities, causing systematic confusion between saccular aneurysms and vascular bifurcations -- a problem especially acute for small lesions (<3 mm), where detection sensitivity falls below 60%. We propose a plug-and-play, topology-aware false-positive reduction framework evaluating the Smooth Euler Characteristic Transform (SECT) -- a directional representation encoding global 3D vascular geometry independently of intensity -- against persistence-based summaries (Persistence Images and Landscapes), tested on a stratified subset of the RSNA 2025 dataset. SECT achieves an AUC of 0.943, substantially outperforming direction-agnostic methods (AUC ~0.68), and exhibits a clinical performance inversion: it excels on the sub-3 mm cohort, maintaining 0.943 AUC and 78.5% sensitivity at 95% specificity. The representation is also scanner-agnostic, achieving 0.927 mean AUC under leave-one-scanner-out (LOGO) validation across four manufacturers. By capturing asymmetric geometric invariants rather than intensity profiles, SECT reliably resolves the primary structural confounder in IA detection, positioning it as a robust downstream filter for hybrid deep-learning diagnostic pipelines.
Chu-Hsuan Lin, Alberto Mario Ceballos-Arroyo, Jisoo Kim +4eess.IV cs.CV
In this work, we present SemanticVessel, a dataset for fine-grained brain vessel segmentation in computed tomography angiography scans. Based on the detailed contrast provided by dynamic 4D-CTA scans, we generate segmentation traces for arteries and veins. We then use intensity-guided region growing to obtain segmentations of the majority of vascular territories in the human brain, which are refined and annotated with 20 unique arterial classes by an expert radiologist. Unlike existing datasets, where minor arteries are discarded as background content, we merge these minor arteries into a generic arterial class. Due to the multiple-phase acquisition of dynamic 4D-CTA, labels for a single phase can be re-used for other phases in the same series, greatly increasing the size of our dataset with no additional annotation cost. The results show that models trained with the additional generic artery class produce better fine-grained segmentations across the board. We will make our code, annotation GUI, and model weights available to the scientific community. Code, weights, and data will be made available on https://github.com/alceballosa/robust-vessel-segmentation