Multi-focus image fusion (MFIF) aims to generate an all-in-focus image from multiple images of the same scene focused at different regions. Most existing deep learning-based methods lack explicit interaction between the source images, which limits their performance and interpretability. This paper presents a novel Clarity Contrast and Similarity Selection Network (CSNet), to bridge direct information exchange for MFIF. Specifically, by contrasting the clarity differences between source images within our proposed Clarity Contrast Attention Module (CCAM), we mutually enhance sharp features while suppressing blurry ones. This allows us to identify the exactly focused regions in each source and locate the focused-defocused boundaries. Moreover, the Defocus Spread Effect (DSE) degrades pixels in all source images around the boundaries. To further refine these ambiguous areas, we introduce a Similarity Selection Strategy, which reconstructs an initial clear image from source images and selects optimal pixels by comparing the similarity among them. Through this interactive approach, CSNet effectively preserves focused regions as well as recovering natural boundaries to fuse an all-in-focus output. Extensive experiments demonstrate that our method achieves state-of-the-art performance both quantitatively and qualitatively. Our code is available on Github: https://github.com/ZYC-HUST/CSNet.
Tracking residual tumor after surgery is essential for catching recurrence early, but automating post-operative glioma segmentation remains a difficult task. Although transformer-based architectures, such as SwinUNETR, achieved impressive results, few studies test how well they generalize across clinical protocols. In this paper, we conduct an ablation study on the MU-GLIOMA-POST and UCSF-ALPTDG datasets and show that the standard Generalized Dice Loss (GDL) is unstable under domain shift: the Whole Lesion (WL) Dice drops from 0.88 on the internal validation set to 0.73 on the external UCSF test set. To address this, we pair brain-masked percentile normalization with voxel-level contrastive learning. We also propose a Subspace-Aware Class Attention (SACA) module that re-calibrates the bottleneck features and raises Enhancing Tumor (ET) sensitivity by 8% (9.1% relative improvement) on internal validation. Ensembling these refinements with nnU-Net brings every stable configuration to a WL Dice of 0.94, and the SACA variant ensemble achieves the best boundary error (HD95) of 2.92 mm on MU-GLIOMA-POST.