Akshay K. Jagadish, Younes Strittmatter, Nori Jacoby +5q-bio.NC cs.AI
Across the sciences, autonomous systems are increasingly being used in closed-loop discovery, proposing new theories and designing and running experiments to test them. This approach is yet to be applied in the field of cognitive science, where the central bottleneck is theory-building: the creative step of turning the accumulated failures of existing models into better ones. Theory generation has remained manual even as data collection, modeling, and experiment design have been automated. We present the Automated Cognitive Scientist (AutoCog), a fully autonomous agentic-AI system that closes this loop. Large-language-model agents advocate competing theories, each expressed as an executable cognitive model, design experiments that best discriminate them, collect behavioral data from participants recruited online, score theories against collected data based on their generative performance, diagnose why they fail, and synthesize a better successor. Repeating this cycle allows them to search the space of theories, models, and experiments. In the domain of decision-making, AutoCog recovered known decision-making strategies from simulated behavior, including unconventional ones, showing that its discoveries are ultimately driven by the data rather than strictly bound by the priors of the underlying language models. When run with human participants, it produced theories that outperformed the established theories it was seeded with and generalized to held-out studies in two different experimental settings. It also surfaced a novel theory of multi-cue decision-making in which choices show diminishing sensitivity to feature values. The distinctive predictions of this theory were confirmed in a preregistered study with new participants. AutoCog demonstrates how an automated discovery system can be used to turn cognitive theory-building into an explicit, executable, and cumulative science.
Scientific discovery can be formulated as an iterative search process over the space of hypotheses and experiments. Contemporary methods navigate this space using heuristics such as MCTS. These algorithms conflate the merit of a hypothesis with the quality of its experimental execution. A promising hypothesis with preliminary execution is therefore ranked below a modest hypothesis whose execution is refined. Moreover, prior methods prune the search logs as the search progresses because the accumulated history outgrows the context window. We propose Agentic Reasoning for Tree Search (ARTS), where we deploy a reasoning language model to navigate this space. The model inspects prior execution logs, diagnoses whether earlier failures arose from faulty implementations or bad hypotheses, and selects the hypothesis to build on next. To mitigate challenges with context length, ARTS uses test-time training to instill the knowledge of search tree in the model weights. Across 22 tasks from MLGym and MLEBench, we show that ARTS outperforms leading algorithms, with over 15.3% relative improvement in the normalized score. With test-time training we show that a Qwen3-4B agent can match performance with closed-source frontier models like Gemini-3 Pro and GPT o3-reasoning with upto 5x lower inference cost. We further observe that on partially observable RL tasks, the test-time trained Qwen3-4B scientist surpasses ARTS with the o3 scientist by rediscovering the human-best recurrent-memory solution that heuristic methods prune away.