Autonomous agents are beginning to carry out machine-learning (ML) research end to end. These agents combine a model backbone with a harness for planning, execution, memory, and verification, but this architecture still leaves domain-specific know-how outside the agent. We call this missing layer operational knowledge, the know-how that separates knowing a method from making it work. That knowledge is not absent from the field. It appears in repositories and papers, but in forms written for human readers and too large to load during a task. Once distilled into compact, verified skills, this knowledge can be reused across tasks rather than rediscovered during each run. We present DisCo, a skill-powered research agent that creates skills and uses them during research. Its distillation runs in two complementary forms: task-agnostic, condensing the field's widely used repositories into reusable skills, and task-oriented, producing the skills a concrete task calls for. The former, applied across the open ecosystem, yields the AREX-Skill Library, with 5,000+ verified skills distilled from 1,000 widely used ML repositories and organized into 20 areas and 178 capability families. With the GPT-5.5 backbone, research harness, and downstream execution budget held fixed, the skill-equipped research agent scores 134.3% higher on MLE-bench, 34.4% higher on PaperBench, 9.2% higher on FrontierCS, and 14.0% higher on PassNet than the same agent without skills. These gains come from adding distilled operating context under that fixed setup.
Autonomous scientific research agents are increasingly applied to end-to-end scientific workflows, including literature review, data analysis, experimentation, and report generation. However, open-ended research tasks often do not clearly specify the analyses, methods, and success criteria required to complete the task. As a result, agents may miss important analyses, use inappropriate methods, or draw conclusions that are insufficiently supported by evidence. To address the problem, we present AutoSciRub, an evaluation-first framework that induces a task-specific executable rubric before research execution, and uses it to guide execution, criterion-level verification as well as iterative revision. AutoSciRub decomposes an underspecified instruction into atomic scientific goals, grounds them in relevant literature and task-visible data, and synthesizes specific, actionable, and verifiable criteria. The resulting rubric makes implicit experimental and evidential requirements explicit, providing guidance for experiments and analyses. During revision, rubric-guided verification identifies unmet criteria and enables targeted refinement of the research report and its supporting artifacts. On ResearchClawBench, AutoSciRub consistently improves all tested configurations, with an average gain of 2.08 points across three backbone LLMs under the fixed Codex harness and 2.95 points across three agent harnesses using a fixed DeepSeek-V4-Flash backbone. On a randomly sampled 20-task subset of AstaBench E2E Discovery, AutoSciRub further achieves an average improvement of 16.8 points across three agent harnesses, while maintaining or increasing the number of successfully completed tasks. These results demonstrate that evaluation-first guidance provides an effective and generalizable control mechanism for autonomous scientific research (Code: https://github.com/zjunlp/AutoSciRub).
Antonis Antoniades, Deepak Nathani, Ritam Saha +6cs.AI
Autonomous AI Research promises to accelerate the scientific progress of machine learning. To realise this goal, current Large Language Model (LLM)-based agents need to go beyond just writing code, to mastering the exploration of simultaneously performant, diverse and novel ideas. To this end, we introduce Heuresis, a framework that abstracts the research pipeline into a set of general and composable primitives, enabling open-ended scientific exploration in machine learning research. We implement six search strategies: a greedy baseline, two archive-based (MAP-Elites, Go-Explore), one evolutionary (Islands), and two divergent (Curiosity, Omni), and evaluate them across three axes (Quality, Diversity, and Novelty) on three domains (LLM Pretraining, On-Policy RL, and Model Unlearning), totalling 3,222 scored runs. We find that completely novel ideas are rare. No idea across our scored runs is rated as "Original", and only a few achieve only "Minor Similarity" to prior work. Moreover, novel ideas never approach the highest-performing known-recipe scores. Across all six strategies and three domains, only one such idea lands in the top-10 by quality. We also observed agents resorting to a variety of reward-hacking techniques during execution (40 confirmed fabrications across 1,628 scored runs), and detecting them was necessary to keep the search faithful to the task. Our results show that while current search and Quality-Diversity strategies enable us to steer where the generated ideas land on the quality, diversity, and novelty axes, they do not expand the quality-novelty frontier. Bridging this gap is the open challenge towards the ultimate goal of perpetual, autonomous scientific progress. Code is available at github.com/a-antoniades/Heuresis.