Constructing causal directed acyclic graphs (DAGs) is a core step in biomedical causal analysis, yet it remains a largely manual process. Analysts must connect study variables to prior literature, evaluate uncertain causal claims, and preserve sufficient provenance for expert review. We present EviDAG, a browser-based system for authoring causal DAGs as auditable, evidence-linked artifacts from biomedical literature. Given free-text descriptions of study concepts, EviDAG creates a reproducible literature snapshot, uses an LLM-based reasoning module to generate structured pairwise causal judgments, links literature-supported judgments to verbatim evidence excerpts, and assembles the judgments into a constraint-checked graph. Each proposed edge includes confidence estimates, provenance, and a reviewable rationale. The interface supports study specification, progress monitoring, evidence review, graph comparison, adjustment-set computation, and export. In evaluations against both compact benchmark DAGs and reference DAGs derived from published literature, EviDAG achieves high edge recall on the literature-based cohort while retaining verifiable evidence trails absent from LLM-only baselines. EviDAG thus reduces the burden of causal DAG curation while making the resulting assumptions auditable, supporting the design, analysis, and interpretation of biomedical studies.
Franco Martino O'Rourke, Ana Trisovic, Dimitris Bertsimascs.LG
A Prior-data fitted Network learns the posterior predictive induced by its training prior; bringing this paradigm to multivariate time-series classification therefore calls for a synthetic generator that produces complete labelled datasets with temporal structure. We introduce a causal prior that synthesizes each dataset from a randomly sampled DAG over typed nodes across two modalities (tabular attributes and time series), natively producing multivariate, multi-class TSC datasets with cross-modal causal structure across channels, timesteps and labels, a regime not addressed by existing synthetic priors. To validate the prior, we finetune TabPFN v2.5 with minimal adaptations and evaluate on 75 UCR/UEA datasets within TabPFN's operating regime. Finetuning on our generator significantly outperforms both the unmodified upstream model and a tabular-only ablation of the same prior (Wilcoxon signed-rank $p=3.0\times 10^{-8}$ on ROC-AUC), isolating the contribution of the cross-modal temporal structure.