VIPER: An Expert-Curated Benchmark for Vision-Language Models in Veterinary Pathology

Pathology vision-language models are advancing rapidly, yet existing benchmarks remain focused on human tissue, particularly oncology, leaving non-human pathology largely unaddressed. This gap is especially important in toxicologic pathology, where microscopic tissue examination of laboratory animals is a core component of preclinical drug safety assessment. To address it, we introduce VIPER, the first expert-curated benchmark for vision-language model evaluation in toxicologic pathology. VIPER contains 1,251 questions associated with 419 H&E-stained rat histology images across seven organ systems, covering multiple-choice, KPrim, and free-text formats. All questions were curated and validated by board-certified veterinary pathologists. In total, we benchmarked 16 models, including two newly introduced veterinary-pathology models, seven human pathology-specialized models, and seven general-purpose frontier models. The results identify a substantial domain gap between veterinary and human pathology, expose the risk of over-diagnosis of normal tissue in frontier models, and show that domain-specific training remains critical for visually grounded predictions. VIPER data and evaluation code are available at https://github.com/mahmoodlab/viper.

Improving Low-Resolution Face Recognition under Limited Data: How Synthetic Data Generation Can Close the Domain Gap

Face Recognition (FR) systems in surveillance settings often encounter Low Resolution (LR) faces, those whose face region falls below the standard 112 $\times$ 112 input size. While labelled High Resolution (HR) training data is abundant, labelled native-LR data, and above all paired native LR/HR data, is scarce. One workaround is to synthesize LR data from the available HR faces, but how much synthesis effort is repaid in recognition accuracy remains unclear. We present a study of simple synthetic generation strategies for a compact, edge device-oriented face recognition system, spanning interpolation-based degradation, knowledge distillation, a Prepended Domain Transformer (PDT), Real ESRGAN-style degradation, and a learned Super Resolution (SR) front-end with an identity-aware loss. We evaluate these strategies on synthetic cross-resolution face benchmarks (LFW, CFP-FP, AgeDB-30) and on TinyFace, a real-world native LR dataset, and expose a synthetic-real gap: the degradation setting that is optimal on synthetic benchmarks is not the one that is optimal on real LR. We find that more synthesis effort does not help monotonically: the learned SR front-end does not surpass a direct feed of the aligned LR image into a strong backbone, while simple interpolation augmentation of a compact backbone is the only synthesis that improves over its own baseline. We conclude that generative methods for LR face recognition must be validated on real LR and against a direct-feed baseline, and release our pipeline at https://idiap.ch/paper/synth-lrfr

Metric-Guided Synthetic Image Data Rendering for Deep Learning compatible with Agentic AI

Deep learning computer vision for scientific applications requires collecting and annotating large datasets in a laborious, expensive and error-prone process. Synthetic data generation through 3D modelling and rendering may simplify this process and increase the accuracy of annotations by generating them programmatically. However, minimising the domain gap between real and synthetic images visually is subjective and lacks systematic quantitative guidance. We present GraNatPy, a Python package with metrics to guide improvement of the rendered scene. We show that quantifiable increase in realism, diversity and size of rendered dataset correlates with improved visual perception of the scene and higher zero-shot performance of an object detection model. Furthermore, we demonstrated using photographs of virological plaque assays that gradient similarity affects performance on small object detection, which can be improved by mixing real and synthetic data. Finally, we turn procedural data rendering into an agentic skill (SynthClaw) to automate the procedural parameter optimisation.

How to Leverage Synthetic Speech for LLM-Based ASR Systems?

In regulated domains such as banking and healthcare, where privacy constraints make real speech costly to collect and retain, synthetic speech from modern text-to-speech (TTS) is an appealing alternative for training automatic speech recognition (ASR) without exposing sensitive customer recordings. Yet a persistent distributional gap between synthetic and real data limits how far it can replace genuine recordings. Prior work largely treats this gap as a black box to be engineered around, but in our work, we instead examine its origin directly by probing a SLAM-ASR architecture. Then, we localise where its LLM backbone separates real from synthetic speech and find the discriminative signal concentrated in the early-to-middle layers, where temporal and prosodic perturbations disrupt it most. We further show that representation-level separability, help, but does not directly predict downstream ASR gains. On the other hand, convolving synthetic audio with room impulse responses (RIRs) narrows the gap not by making synthetic speech sound cleaner or more natural, but by reproducing the acoustic irregularities of real recordings. Translating these findings into the training procedure, by adding a layer-selection module combined with RIR augmentation matches a fully real-data baseline using only 25% of the real speech (13.6h) and surpasses it at all higher proportions.

Mind the Gap: Quantifying the Domain Gap in Cross-Sensor Diffusion Super-Resolution

Demand for high-resolution satellite imagery has increased interest in super-resolution (SR) to bridge the spatial resolution gap between freely available missions such as Sentinel-2 and commercial systems like PlanetScope. Because no sensor provides true paired low- and high-resolution observations, SR models are usually trained on synthetically degraded data, creating a domain gap on real cross-sensor imagery. In this work, we provide the first systematic study of how this synthetic-to-real mismatch affects the performance of modern diffusion-based SR models. Using a large, geometrically and temporally aligned dataset of Sentinel-2 and PlanetScope imagery, we evaluate five state-of-the-art diffusion architectures under controlled experimental settings. We also introduce LPIPS-Sat, a domain-adapted perceptual metric based on Sentinel-2 self-supervised features. Our results show two persistent challenges: synthetically trained models degrade sharply on real pairs, while models trained on real cross-sensor data exhibit optimisation difficulties and struggle to adapt to the physical and radiometric diversity. These findings highlight a key limitation of current SR and motivate methods that disentangle super-resolution from domain adaptation.

Efficiently Linking Real Scenes with Synthetic Data Generation for AI-based Cognitive Robotics and Computer Vision Applications

AI vision models are a driving factor for the potential use case scenarios of cognitive robotics within in the industry and household applications. A large array of methods from semantic environment analysis towards 6D and grasping pose estimation have been proposed based on the latest AI achievements. However, such advancements require further strong and efficient methods w.r.t. training data and AI-architectures, which are capable in synergy to tackle current challenges, precision limits, and scalability beyond domain gaps. In this paper, we discuss these current limits and trends in the related state-of-the-art which are challenging those. Further we discuss our current work in progress on bridging the domain gap between simulations and real world applications by linking those in the training data generation.

SADGE: Structure and Appearance Domain Gap Estimation of Synthetic and Real Data

We propose SADGE, a quantitative similarity metric that predicts the performance of synthetic image datasets for common computer vision tasks without downstream model training. Estimating whether a synthetic dataset will lead to a model that performs well on real-world data remains a bottleneck in model development. Existing evaluation metrics (e.g., PSNR, FID, CLIP) primarily measure semantic alignment between real and synthetic images (Appearance Similarity Score). Less commonly, structural similarity between images is considered to assess the domain gap (Geometric Similarity Score). However, to the best of our knowledge there exists no studies that evaluate which similarity metric is the best downstream predictor for a given synthetic dataset. In this paper, we show over a wide variety of different synthetic datasets and downstream tasks that neither appearance nor geometry alone can reliably predict downstream performance; rather, it is their non-linear interplay that dictates synthetic data utility. Specifically, we measure how commonly used Appearance and Geometric Similarity metrics computed between synthetic and real images correlate with downstream performance in object detection, semantic segmentation, and pose estimation. Across five public synthetic-to-real benchmark families and 15 dataset-level variants (79k image pairs), SADGE achieves the strongest association with downstream transfer performance under both linear and rank-based criteria, reaching Pearson r=0.88 and Spearman rho=0.77. We compute for each combination of geometry-based methods and appearance-based approaches SADGE scores across all benchmark families. The best configuration is obtained by fusing DINOv3 appearance similarity with MASt3R geometric consistency through a constrained bilinear interaction, outperforming both the strongest geometry-only baseline and the strongest appearance-only baseline .

BMD-45: A Large-Scale CCTV Vehicle Detection Dataset for Urban Traffic in Developing Cities

Robust vehicle detection from fixed CCTV cameras is critical for Intelligent Transportation Systems. Yet existing benchmarks predominantly feature relatively homogeneous, highly organized traffic patterns captured from ego-centric driving perspectives or controlled aerial views. This regional and sensor view bias creates a significant gap. Models trained on datasets such as UA-DETRAC and COCO struggle to generalize to the dense, heterogeneous, disorganized traffic conditions observed in rapidly developing urban centers in emerging economies. To address this limitation, we introduce BMD-45, a large-scale dataset comprising 480K bounding boxes annotated over 45K images captured from over 3.6K operational Safe City CCTV cameras. BMD-45 contains 14 fine-grained vehicle categories, including region-specific modes such as auto-rickshaws and tempo travellers, which are not present in existing benchmarks. The dataset captures real-world deployment challenges, including extreme viewpoint variation, occlusion, and vehicle density . We establish comprehensive baselines using state-of-the-art detectors and reveal a striking domain gap: models fine-tuned on UA-DETRAC achieve only 33.6% mAP@0.50:0.95, compared to 83.8% when trained in-domain on BMD-45, representing a 2.5x improvement that persists even when accounting for novel vehicle classes. This performance gap underscores the critical need for geographically diverse traffic benchmarks and establishes BMD-45 as a baseline for developing robust perception systems in underrepresented urban environments worldwide. The dataset is available at: https://huggingface.co/datasets/iisc-aim/BMD-45.