Quantifying the Relationship Between Clinical Safety and Environmental Impact in Therapeutic LLMs

The deployment of large language models (LLMs) in mental health contexts raises questions about the relationship between clinical safety and environmental cost. In this paper, we examine this relationship by combining K-Bench clinical safety scores with EcoLogits life-cycle assessment estimates across 47 supported model configurations. We evaluate model performance and environmental impact across four dimensions: energy use, carbon emissions, water consumption, and abiotic depletion. The results indicate a non-linear trade-off at the upper end of the safety distribution: a 2.61 percentage-point increase in clinical safety score corresponded to an approximately 60-fold increase in estimated energy use per million output tokens. Row-level analyses further suggest that additional test-time compute did not consistently improve clinical safety and, in some configurations, was associated with lower clinical safety scores. These findings suggest that relying solely on larger models or additional inference-time computation may be an inefficient strategy for improving safety in therapeutic AI systems. We discuss the implications for sustainable deployment and highlight dynamic model selection, including model cascading, as a potential approach for reducing environmental impact while preserving clinical performance in higher-risk cases.

Life Cycle Assessment of Pre-training the Lucie 7B Open-Source Large Language Model on the Jean Zay Supercomputer

The environmental impact of training large language models (LLMs) is increasingly scrutinised, yet most published estimates focus on operational energy and disclose little about manufacturing (embodied) emissions, water consumption, or the underlying highperformance computing (HPC) infrastructure. We present a life cycle assessment (LCA) of the pre-training of Lucie 7B, an open-source multilingual Foundation Model developed by the OpenLLM-France consortium and trained on the NVIDIA H100 partition of the Jean Zay supercomputer operated by IDRIS (CNRS). The assessment is framed by the AFNOR SPEC 2314 "Frugal AI" reference and applies the Labos 1point5 methodology for greenhouse gas(GHG) accounting in computing. The study scope extends from data preparation to model validation, and integrates the full life cycle of the hardware infrastructure: manufacturing (including raw-material extraction), use (compute, temporary storage, system administration, cooling), and end-of-life. We report (i) an annual footprint of 417.5 tCO2eq for the Jean Zay H100 partition, split almost equally between manufacturing and operation; (ii) an effective intensity of 36.7 gCO2eq per H100 GPU-hour; (iii) a total training footprint of 21 tCO2eq for Lucie 7B (574 564 H100 GPU-hours), inclusive of amortised hardware manufacturing; (iv) on-site water consumption of approximately 76m3 for the training campaign and an annual Water Usage Effectiveness (WUE) of 0.07 L/kWh for IDRIS; (v) a heat-reuse factor (ERF) of 0.37 thanks to waste-heat recovery into the urban heating network. The study contributes one of the few publicly documented LCAs of an LLM training campaign that explicitly couples operational data with embodied emissions decomposed by subsystem (compute, storage, power chain, cooling), and discusses the implications for the design of frugal-by-construction AI systems in Europe.

The Rising Unsustainability of AI Graphics Cards Production

The rapid advancement of Artificial Intelligence (AI) has been accompanied by significant increases in computational and environmental costs, driven by large-scale investments in AI infrastructure, hardware, and software. In particular, graphics cards have become central to AI training, with frequent hardware updates required to meet escalating computational demands. However, the environmental damages of graphics cards production remain understudied. This study addresses this gap by estimating the environmental damages associated with graphics cards production over the past decade (2013-2025). We analyze trends in energy consumption, carbon emissions and resource depletion. We compile and provide a dataset documenting the environmental damages of NVIDIA workstation graphics cards production since 2013. Our analysis of this dataset reveals a steady increase in production-related impacts over the period. Our finding highlights the need for greater transparency in life-cycle data, a persistent challenge in AI environmental assessments. While operational efficiency improvements (e.g., energy-efficient training, carbon-aware computing) are often prioritized, our results underscore that production-related impacts are also escalating and cannot be overlooked. The AI community must move beyond incremental optimizations and confront the necessity of sufficiency. This shift may demand structural changes such as policy interventions, hardware design for longevity, and cultural shifts away from perpetual growth and increased performance.

The Hidden Water Geography of U.S. Hyperscale Data Centers in the AI Era

Water use by data centers is routinely reported as a single footprint, but water is consumed through two physically distinct pathways: at the site for cooling and in the power system that generates electricity. We mapped both pathways for 472 U.S. hyperscale facilities by linking facility locations to electricity regions, hydrologic basins, and water-stress data. Under baseline assumptions, operational water consumption totals approximately 300 GL yr^-1 (range 205-451 across scenarios), with electricity-related water contributing three-quarters of the total. The two pathways produce different hotspot geographies: direct cooling burdens concentrate in stressed western and south-central basins, whereas electricity-related burdens concentrate in a few eastern grid regions with fossil-heavy supply. Just 3 of 24 hosting balancing authorities account for 59% of electricity-related water. Separating pathways identifies which decisions matter where: cooling design and water sourcing locally, electricity planning and procurement regionally

Assessing the Carbon Emissions and Energy Consumption of U.S. Hyperscale Data Centers

The rapid proliferation of hyperscale data centers (HDCs) in the US, mainly driven by the adoption of artificial intelligence, has raised concerns about this industry's environmental footprint. We compiled facility-level information on 403 US hyperscale data centers operating between May 2024 and April 2025 and estimated their electricity consumption, electricity sources, and attributable CO2 emissions. Across different facility-load scenarios, these HDCs consumed approximately 68-99 TWh of electricity and were associated with about 37-54 million metric tons of CO2. Under the central scenario, HDC electricity demand corresponded to approximately 1.8% of total US electricity consumption, with roughly 54% of attributed generation supplied by fossil-fuel sources. The HDC electricity-weighted average carbon intensity was approximately 545 gCO2/kWh, about 48% above the contemporaneous US national grid-average carbon intensity of 370 gCO2/kWh. Our approach provides an attributional tool for assessing the environmental footprint of hyperscale data centers using the most recent EPA eGRID plant-level data.