AOI-Net: Structural Face AOI-Guided Eye-Gaze Track Representation Learning for Autism Spectrum Disorder Detection

Eye-movement tracking has emerged as a promising non-invasive approach to Autism Spectrum Disorder (ASD) screening, with systematic differences in attentional allocation and revisit behaviors observed during socially interactive tasks. Existing computational methods typically characterize eye-movements using discrete gaze trajectories and fixation events, yielding representations dominated by short-range temporal dynamics and limiting models that primarily emphasize long-range dependencies. Meanwhile, gaze behavior is naturally organized across semantically meaningful Areas of Interest (AOIs), whose attention allocation and transitions provide important structural cues, yet their relationships are rarely modeled explicitly. To address these limitations, we propose a structural face AOI-guided Eye-Gaze Track Network (AOI-Net) that jointly models short-term temporal dynamics and AOI-level structural organization. A network gating mechanism adaptively integrates the complementary temporal and structural representations according to their contributions to gaze-behavior characterization. To mitigate the pronounced class imbalance commonly encountered between individuals with ASD and Typically Developing (TD) participants in clinical datasets, class-distribution-aware learning is further employed to facilitate discriminative embedding learning under skewed class distributions. Experiments on a unique and large-scale clinical eye-tracking database comprising eight stimulus subsets and more than 1,300 participants show that AOI-Net consistently outperforms state-of-the-art methods. The proposed framework also enables interpretable gaze-behavior modeling and provides a practical basis for scalable AI-driven ASD screening in real-world healthcare. The code is available at https://github.com/Zhanpei-ai/CIM-AOI-Net/tree/main/Code

Consensus Clustering of Free-Viewing Gaze Data: New Insights into Human-Information Interaction

Free-viewing gaze data provides a rich, task-free window into human visual attention. Conventional exploratory data analysis of the data provides user attention patterns through fixations and areas of interest. However, despite the richness of this gaze data, its human-information interaction (HII) patterns are understudied. We address this gap using consensus clustering of gaze data with respect to users and stimulus characteristics. We present a novel end-to-end unsupervised ensemble learning system for consensus clustering of free-viewing gaze datasets, EnsembleGaze. With a goal of characterizing the user behavior and stimulus type, we propose a feature engineering step based on statistical descriptors of fixation-based distributions. EnsembleGaze involves consensus voting of selected clustering methods implemented on the feature vector to compute the co-association matrix. Using the separate consensus clustering of users and stimuli as a baseline, we further propose two high-dimensional clustering strategies for determining gaze clusters based on joint user and image characterization. They are consensus subspace clustering and spectral biclustering. Clustering performance is evaluated using selected standard metrics and is further interpreted through image-level properties. Our system provides a replicable method for the unsupervised analysis of fixation behavior in scene perception research. Our results show that image stimuli groupings are highly consistent across methods, reflecting a robust ambient-versus-focal viewing mode distinction, whereas user groupings are image-context-dependent, a structure that only biclustering and the two-step conditional approaches are architecturally capable of recovering. Testing on the publicly available datasets revealed dataset-specific patterns, with each offering complementary insights through distinct clustering strategies.