Zixiang Tong, Lehu Bu, Jin Yangcs.CV cond-mat.mtrl-sci
Digital volume correlation (DVC) provides three-dimensional full-field displacement measurements from volumetric images, but how the internal resolution of a machine-learning-based DVC model affects accuracy and operating range remains poorly understood. Here, we present RAFT-DVC, a resolution-aware family of recurrent all-pairs field transforms (RAFT)-based DVC solvers with encoder downsampling factors s = 2, 4, and 8. Using a matched design, we find that the three solvers localize displacement to approximately 0.017 feature-grid voxel, giving an empirical raw-volume error scaling of approximately 0.017s voxel. The solvers exhibit complementary operating regimes governed jointly by displacement reach and volumetric-texture compatibility. Synthetic benchmarks show that RAFT-DVC achieves errors of the same order as tuned classical DVC under fine-texture, small-to-moderate-displacement conditions and becomes competitive or advantageous under coarse-texture, large-displacement conditions. Frequency-swept tests quantify deformation spatial resolution, while tiled inference enables dense estimation on large volumes. Evaluation on confocal volumetric images acquired during indentation illustrates the importance of matching solver operating regime to deformation magnitude and image texture. Tests on micro-CT images of elastomeric foam, despite training only on particle-labeled synthetic data, provide evidence of cross-texture transfer. We also identify coordinate-order inconsistencies in three-dimensional RAFT correlation sampling and introduce a non-cubic impulse test to verify sampler geometry independently of network training. Correcting the sampler improves native-input accuracy and generalization to unseen volume dimensions. Together, these results establish RAFT-DVC as a fast, resolution-aware framework for dense DVC with characterized accuracy and operating regimes.
Pedro Lemes Sixel Lobo, Eric Tokuda, Kuruvilla Joseph Abraham +4physics.soc-ph cs.LG stat.AP
Urban food environments may reflect broader socioeconomic inequalities, but district-level evidence remains limited in Brazilian cities. This study examined whether indicators of food retail and street-market availability discriminate between levels of social vulnerability across the 96 districts of São Paulo. We conducted an exploratory cross-sectional ecological analysis integrating the São Paulo Social Vulnerability Index (IPVS), establishment records from the Relação Anual de Informações Sociais (RAIS), and street-market data from CAISAN. Census-sector information was aggregated at the district level. Twenty districts without an IPVS classification were excluded, resulting in 76 observations. The outcome distinguished districts classified as IPVS level 1 from those classified as levels 2--7. Predictors described the densities of healthy and unhealthy food establishments, the number of street markets, and the availability of establishments selling fresh or in natura food. Eight conventional machine-learning classifiers were evaluated using leave-one-out cross-validation. Reported mean F-scores ranged from 0.62 to 0.75, with XGBoost obtaining the highest value. In the Random Forest model, the densities of healthy and unhealthy food establishments jointly accounted for approximately 60% of the total impurity-based feature importance. These findings indicate that publicly available food-environment indicators contain information associated with the district-level distribution of social vulnerability. However, the small ecological sample, class imbalance, outcome binarization, and cross-sectional design limit predictive generalization and preclude causal or household-level interpretations.
These lecture notes form the first part of a master's-level course on advanced numerical linear algebra. Their aim is not only to present the classical algorithms, but to show why the subject has become considerably more central than it was a generation ago. Numerical linear algebra grew up alongside the numerical solution of partial differential equations, and for a long time that is where its large sparse systems came from. Ranking the nodes of a network, assimilating observations into a weather forecast, and fitting a model to a large noisy data set now lead to problems of the same kind: too large to factorise, structured, and accessible only through matrix-vector products. Strikingly few ideas are needed for all of them. Each chapter therefore develops a standard topic and then puts it to work outside its original setting. We treat norms, factorisations, conditioning and floating-point arithmetic; sparse matrices arising from finite differences, from graphs and from machine learning; stationary iterations and the smoothing property; the conjugate gradient and Lanczos methods, with spectral clustering and regularisation by early stopping; Arnoldi and GMRES, with PageRank and large least squares; and finally preconditioning, Schwarz domain decomposition and multigrid. We assume a first course in linear algebra. Every section closes with a summary of what should be retained and every chapter with exercises, several drawn from past examinations. Accompanying Python code reproduces the numerical illustrations.
Osteoarthritis (OA) is a progressive chronic joint disease resulting in a breakdown of articular cartilage and bone when damaged joint tissues are not able to normally repair themselves. The aim of this pilot research study is to understand the pain severity for OA from patients' primary care Electronic Medical Records (EMR), both from the structured medical data and the unstructured chart note data using information extraction, natural language processing and machine learning techniques. We propose SPaDe, a Synonym-based Pain level Detection tool to categorize patients into having mild or moderate-to-severe pain to understand diagnosis and treatment methods based on only the pain related expressions in the unstructured chart note. Expressions are subjective, objective, and influenced by cultural background and demography which poses a difficult challenge. Therefore, we improve the model by incorporating the medication information from the structured EMR data and pain scale related information from the chart note to propose an integrated pain level detection tool for OA called PLeDO. With the help of human labeled gold standard data, we demonstrate that both SPaDe and PLeDO can detect mild and moderate-to-severe pain from the EMR data to analyze and potentially improve the quality of care in primary care setting.
Cardiovascular disease is still one of the main causes of death around the world. Acute myocardial infarction (MI), or heart attack, claims millions of lives each year. MI happens when blood flow to the coronary arteries is blocked or reduced, which causes permanent damage to the heart muscle. Without treatment, this can lead to cardiac arrest, where the heart stops pumping blood to the organs, resulting in organ failure and death. Even survivors often face serious problems like heart failure, pulmonary edema, and asystole. Research shows that 5 to 10 percent of survivors die within the first year after an MI, and nearly half need to be hospitalized again. Early thrombolytic treatment leads to better outcomes, so there is a clear need for faster and more accurate ways to diagnose MI. Right now, doctors usually review patient history and use their own experience to find the causes of MI. This process takes a lot of time and can be inconsistent. Detecting MI accurately and quickly can help patients take better care of themselves and prevent fatal events. In this study, we introduce an automated model to predict deadly outcomes of MI and help doctors understand important biomarkers linked to its complications. This approach aims to make diagnosis clearer, faster, and more affordable. The process includes preparing the data, filling in missing values, and handling imbalanced data using SVMSMOTE, ADASYN, and class-weighted methods. We use wrapper and embedded feature selection to find the most important variables, then scale the features for consistency. The model combines Logistic Regression, Random Forest, Light-GBM, and Bagging SVM, and is further improved with an artificial neural network to increase accuracy. We evaluate all models using precision, recall, and other key measures to find the best option for clinical use.
Gervais Hatungimana, Abdun Naser Mahmood, Mohammad Jabed Morshed Chowdhurycs.CR cs.LG
Most corporate workplace environments enforce policies and technical controls that limit the storage of sensitive data on client endpoints. Consequently, ransomware operators have evolved variants that expand their attack surface from local systems to network drives and shared storage resources. As traditional endpoint detection mechanisms focus primarily on local system behaviour, a compromised client can impact remote file servers, such as by encrypting shared data, without directly triggering behavioural changes on the servers themselves. In this paper, we propose a hybrid detection framework for detecting crypto-ransomware intrusion within integrated file server and client environments. The framework is based on a new technique referred to as Region of Interest (RoI) to analyse network traffic and extract Indicators of Compromise (IoCs). The IoC repository serves as an additional ruleset to enhance existing security tools such as EDRs and IDSs, while RoI-derived features are used to train an ML model to detect highly evasive variants. This study incorporates a broader set of ransomwares families and carefully selected benign behaviors based on domain expertise, ensuring coverage of common user actions that could interfere with ransomware detection. Beyond IoCs, which operate in a signature-based manner, our machine learning module achieves a detection precision of 99.64%, with a 0% false negative rate (FNR) and a minimal false positive rate (FPR). Furthermore, the proposed method enables early detection, identifying ransomware intrusions before significant damage occurs, achieving an accuracy of 99.44%.
Short-term environmental exposures have been linked to cognitive and behavioral outcomes, although many reported associations may reflect broader geographic and contextual differences. Using longitudinal data from the All of Us Research Program (2018--2024), we linked daily weather and air-pollution exposures to repeated attention-related and subjective cognitive outcomes. Associations were evaluated using pooled, fixed-effects, lagged, and event-study analyses. Additional machine-learning analyses were conducted to explore potential heterogeneity and latent psychosocial structure. Replication analyses were performed using the 2024 Behavioral Risk Factor Surveillance System (BRFSS). Several environmental exposure measures showed small associations with cognitive outcomes in pooled analyses, but most attenuated substantially after accounting for within-location temporal variation. Mediation, sensitivity, and machine-learning analyses yielded similar conclusions. In contrast, mental-health burden, loneliness, and social functioning were consistently associated with subjective cognitive difficulty and exhibited substantially larger effect sizes than environmental exposures. Similar patterns were observed in BRFSS. Exploratory AI-assisted analyses yielded findings broadly consistent with the primary longitudinal analyses. These findings suggest that short-term environmental perturbations may have limited associations with cognitive outcomes after accounting for within-location variation, whereas psychosocial factors appear to be more consistently associated with subjective cognitive burden.
Risk stratification for advanced colorectal polyps typically relies on colonoscopy and/or pathology findings. However, there is growing interest in whether non-invasive features available prior to colonoscopy can help identify patients at higher risk. Such approaches may enhance clinical decision-making by prioritizing surveillance for individuals most likely to harbor high-risk polyps, when colonoscopy resources are limited while potentially reducing unnecessary procedures in lower-risk patients. Importantly, the use of non-invasive, pre-procedural information may also help promote more equitable access to risk stratification, particularly in settings where colonoscopy resources are limited or unevenly distributed. We aimed to develop and externally validate machine learning models to predict high-risk colorectal polyps using only non-invasive, pre-colonoscopy demographic, clinical, and behavioral features in a diverse, predominantly African American, urban cohort. We conducted a retrospective cohort study using demographic, lifestyle, and comorbidity data from patients who underwent colonoscopy at Howard University Hospital to develop and validate several machine learning models, including neural networks, random forest, support vector machines (SVM), Naive Bayes, logistic regression, decision trees, k-nearest neighbors (KNN), and XGBoost, for predicting high-risk colorectal polyps. High-risk polyps (HRP) were defined as villous or tubullovillous adenomas, high-grade dysplasia, polyps >= 10 mm in size, and/or the presence of >= 3 polyps per procedure; all other cases were classified as low-risk polyps (LRP). The dataset included 4,681 patients from 2015-2022 used for internal validation and 1,562 patients from 2023-2024 used for external validation.
Label-free, image-based cellular mechanophenotyping in microfluidic devices provides a high-throughput method for single-cell profiling. However, while complex microchannels (e.g., hyperbolic geometries) reveal transient deformation dynamics under continuous extensional stress, the resulting high-dimensional feature spaces are highly susceptible to hydrodynamic artifacts. Flow rate variations often distort discriminative boundaries, linking feature distributions to fluid conditions rather than intrinsic biology. To overcome this, we introduce a stability-guided analytical framework that decouples flow-induced noise from authentic mechanobiological signatures. We tracked the morphodynamic, kinematic, and intracellular optical-density trajectories of healthy and malignant ovarian cells to build a 93-dimensional feature space. Using a cross-flow screening strategy based on structural consistency and statistical persistence, we isolated robust descriptors, creating task-adapted subsets (20 features for binary classification; 25 for cancer subtyping). Variance-attribution analysis confirmed the neutralization of flow-conditioned artifacts; notably, flow-associated variance in the primary principal component fell from 69.9% to 9.3% in the subtyping task. We also found that macroscopic binary discrimination depends on bulk kinematic transitions, while clonal subtyping requires localized intracellular optical heterogeneity. These optimized subsets maintained diagnostic fidelity across multiple machine learning architectures and restricted sampling conditions. This framework establishes a robust, flow-independent foundation for continuous dynamic phenotyping.
This study investigates the application of machine learning models to predict exam outcomes using physiological data collected during examination sessions. Physiological stress indicators, including electrodermal activity, heart rate, and skin temperature, were analyzed to uncover their association with academic performance. A variety of machine learning approaches were employed, ranging from standard models like logistic regression, random forest, and support vector machines to more advanced architectures, including transformers, long short-term memory (LSTM), and gated recurrent unit (GRU) models. This diversity aimed to capture the complex interactions within the data effectively. A key focus was assessing the adaptability of transformers in processing numerical data and evaluating their performance in this novel context. Standard performance metrics, such as accuracy, precision, recall, and F1-score, were used to compare model efficacy. The experimental results demonstrate that while deep learning models generally excel at capturing complex relationships in physiological data, simpler models like random forests can sometimes achieve superior performance while offering computational efficiency and interpretability. Furthermore, transformers demonstrated notable versatility, showcasing performances comparable to those of the LSTM and GRU models. This research underscores the importance of experimenting with a broad class of models that align with the objectives of the problem at hand, balancing precision, efficiency, and interpretability. By elucidating the relationships between physiological signals and academic performance, this study contributes to understanding stressors affecting students' mental health. It further promotes leveraging physiological data to enhance student well-being and academic outcomes.
Antonio Pagliaro, Anna Anzaloneastro-ph.IM stat.ML
Time series analysis is a fundamental component of machine learning, especially in astrophysics and cosmology where temporal data abound. This chapter provides a pedagogical review of time series analysis techniques from a machine learning perspective. We cover the basic concepts of time series (stationarity, autocorrelation, seasonality), classical statistical models (autoregressive, moving average, ARIMA, exponential smoothing, state-space models), and modern machine learning approaches. In particular, we discuss how traditional statistical methods lay the groundwork, and then explore machine learning methods for time series, including feature-based regression, tree-based ensemble methods, hidden Markov models, Gaussian processes, and deep learning models (recurrent neural networks, convolutional networks, transformers). Throughout, we illustrate with examples drawn from multiple domains (e.g. astronomy, weather forecasting, finance) to emphasize common principles. The goal is to equip readers with both the theoretical understanding and practical context to apply machine learning techniques for time series analysis in their research.
Justin Berman, Francois Charton, Andres Luna +2hep-ph cs.LG hep-th
In this paper, we use machine learning to discover a new seeding strategy for integration-by-parts reduction of Feynman integrals, which is a frequent bottleneck in state-of-the-art calculations in theoretical particle and gravitational-wave physics. Our strategy allows us to reduce multi-loop integrals with large numerator powers via essentially the standard Laporta algorithm but with a sparse selection of seed integrals that grows only linearly with the numerator power, whereas existing strategies lead to growth with a polynomial power that increases with the complexity of the integral being reduced. The seeds are restricted to a thin tube-like region that connects the target integral to the master integrals along a zigzag path. We demonstrate the power of our approach by reducing non-planar 2-loop 5-point integrals of rank 20 with numerical kinematics over a finite field, which is prohibitively difficult for the Laporta algorithm with conventional seeding. Going beyond individual integrals, we further demonstrate the reduction of a complete set of top-level rank-10 integrals by dividing the target integrals into several chunks, each of which can be solved by our sparse seeding strategy with considerably less time and a significantly lower memory footprint than other state-of-the-art strategies, making the approach well-suited for phenomenological applications. We provide a proof-of-principle implementation on GitHub at https://github.com/andreslunagodoy/tube_seeding.
Creativity is a complex cognitive ability that relies on knowledge organisation and retrieval from semantic memory. Yet most research uses a single task to measure it, capturing only a fraction of this complexity. This study investigates multiplex networks - layered semantic networks obtained from six cognitive tasks - as a more comprehensive approach to modelling the associative knowledge underlying creativity. We collected data from N=518 individuals from four countries (Austria, USA, Singapore, Italy). From their responses to verbal fluency, sentence-chain, free association, and narrative writing tasks, we constructed semantic networks and assembled them in a multiplex structure. AI persona-based responses provided a comparison baseline. Structural reducibility analyses showed that different task layers captured distinct, non-redundant information about semantic organisation, supporting the use of multiple tasks over any single one. The networks from high- and low-creative groups remained structurally distinct, while AI-generated networks showed near-identical structures regardless of creativity group. Finally, we used 12 features (network measures, emotional scores, and spreading activation simulations) in a machine learning model using ridge regression to predict individual creativity scores. The combination of structurally similar layers, as identified in the previous stage, improved a proof-of-concept prediction accuracy by 50%. Structural measures showed the highest feature importance, with spreading activation dynamics providing additional predictive power. Together, these findings indicate that multiplex semantic networks capture a richer, cross-cultural picture of associative knowledge underlying creativity. We also release our diverse dataset and code to foster diverse computational approaches within the creativity community.
June-Woo Kim, Kangwook Jang, Minu Kim +1cs.SD cs.AI cs.LG
Ambulatory neck-surface acceleration enables non-invasive monitoring of vocal hyperfunction, yet robust biomarkers for its subtypes remain limited. This study investigates the NeckVibe Challenge dataset to distinguish phonotraumatic (PVH) and non-phonotraumatic (NPVH) from healthy controls. We propose a hierarchical feature engineering framework comprising: (i) static, (ii) dynamic, (iii) ratio-based, (iv) coupling features capturing source filter interactions. While univariate statistical analysis shows strong separability for PVH but limited significance for NPVH, our machine learning pipeline, tailored for high-dimensional feature integration, identifies that coupling features are crucial for both tasks. We achieve an AUC of 0.891 for PVH and 0.728 for NPVH, suggesting that while PVH is near-linearly separable, NPVH discrimination benefits from modeling non-linear feature interactions.