From Textual Requirements to Microservice Architectures - A Comprehensive Evaluation of LLM-Based Design Synthesis

Microservice architectures have become dominant for modernizing monolithic systems, yet identifying appropriate services remains challenging and largely manual. Existing decomposition approaches are predominantly code-centric, limiting applicability in early design stages where only textual requirements are available. Despite advances in Large Language Models (LLMs), limited empirical evidence exists on their ability to synthesize complete microservice architectures from natural-language requirements, including service definitions and inter-service interactions. This study investigates whether an LLM can bridge requirements engineering and architectural design, generating architectures solely from textual requirements and evaluating structural agreement and perceived quality of results. We conduct a mixed-method study using OpenAI o3 under zero-shot (ZS) and few-shot (FS) prompting across two systems (Bookstore, PetClinic), one execution per system/condition. Architectures are evaluated through (i) comparison with reference architectures using precision, recall, and F1-score for service identification and communication recovery, and (ii) a blinded expert assessment of correctness, completeness, modularity, and plausibility, plus open feedback synthesis. OpenAI o3 identifies services with higher agreement under FS prompting (F1 = 0.79 for ZS versus = 0.97 for FS). Communication recovery is more challenging: ZS produces dense architectures with high recall but low precision (F1 = 0.61), while FS improves agreement, reaching F1 = 0.82 and reducing unsupported dependencies. Expert evaluation corroborates these results, with FS architectures perceived as more modular, coherent, and plausible than ZS outputs. OpenAI o3 shows potential for requirements-driven synthesis when guided by exemplar prompting. Results are model- and context-specific from two small systems, not model-independent proof.

KAYRA: A Microservice Architecture for AI-Assisted Karyotyping with Cloud and On-Premise Deployment

We present KAYRA, an end-to-end karyotyping system that operates inside the operational constraints of a clinical cytogenetic laboratory. KAYRA is architected as a containerized microservice pipeline whose ML stack combines an EfficientNet-B5 + U-Net semantic segmenter, a Mask R-CNN (ResNet-50 + FPN) instance detector, and a ResNet-18 classifier, orchestrated through a cascaded ROI-narrowing strategy that focuses each downstream model on the chromosome-bearing region. The same container images are deployed both as a cloud service and as an on-premise installation, supporting clinical environments where patient-data egress is not permitted as well as those where it is. A pilot clinical evaluation against two commercial reference karyotyping systems on 459 chromosomes from 10 metaphase spreads shows segmentation accuracy of 98.91 % (vs. 78.21 % / 40.52 %), classification accuracy of 89.1 % (vs. 86.9 % / 54.5 %), and rotation accuracy of 89.76 % (vs. 94.55 % / 78.43 %). KAYRA improves over the older density-thresholding reference on all three axes (p < 0.0001 for segmentation and classification by Fisher's exact test on chromosome-level counts), and on segmentation also against the modern AI- supported reference (p < 0.0001); on classification the difference vs. the modern AI reference is not statistically significant at the present test-set size (p = 0.34). The system reaches TRL 6 maturity and integrates the human-in-the-loop expert-review workflow that diagnostic cytogenetic practice requires. The thesis of this paper is that a multi-model cytogenetic AI service can be packaged as a microservice architecture supporting flexible deployment - cloud-hosted or on-premise - while delivering strong empirical performance on a pilot clinical evaluation.