Towards Autonomous and Auditable Medical Imaging Model Development

Large language model (LLM) agents are beginning to automate machine learning engineering (MLE) by coupling planning, code execution, debugging, and empirical feedback. Translating this capability to medical imaging remains difficult because each task imposes modality-specific experimentation and strict requirements for validation protocols and prediction artifacts. Here we introduce AMID, an autonomous multi-agent framework for medical imaging model development. AMID first proposes Data-Conditioned Method Planning, which refines coarse task-level search spaces into executable, parallelizable method lanes grounded in task-specific data analysis and runnable medical-imaging resources. It then develops Verification-Guided Two-Stage Optimization, moving from broad early exploration of diverse method lanes to selective exploitation of promising candidates while enforcing strict verification of validation protocols, metric computation, and prediction artifacts throughout the optimization. Across 20 medical imaging challenge tasks spanning diverse modalities and prediction types, AMID outperformed evaluated general-purpose MLE systems and, on several tasks, approached or matched strong human-designed challenge solutions. These results suggest that AMID can turn task-specific medical imaging model development from bespoke manual engineering into an agentic workflow for producing high-performing and auditable model artifacts across heterogeneous tasks.

From Failure Taxonomy to Intervention: A Diagnostic Methodology for Industry-Scale AVLM in Video and Live-Streaming Platform Moderation

Industry-scale video and live-streaming moderation imposes requirements that are difficult to satisfy with generic pretrained public models or external APIs, including adaptation to platform-specific data distributions, policy-specific objectives, and product-level safety constraints. As a result, platforms must undertake internal model development, naturally turning to shared public research for guidance. However, existing multimodal foundation-model studies primarily report architectures, training recipes, data scaling strategies, and benchmark results, but provide less systematic guidance on how failures should be localized and translated into targeted model-development interventions. Interventions are essential because deployment failures are rarely self-explanatory. Similar failures can originate from different causes. Without targeted interventions, improvement reduces to heuristic trial-and-error, where benchmark improvements are weakly attributable, and failures are difficult to trace to their underlying causes. To address this gap, we present a diagnostic methodology for industry-scale Audio-Visual-Language Models AVLM development. The methodology maps model failures into a taxonomy of observable failure signatures and links each class of failure to an intervention space. We instantiate this methodology across the development and alignment lifecycle of an AVLM foundation model for a large-scale video and live-streaming platform. The resulting system supports over 100 regions and is designed for noisy, ambiguous, and highly diverse content drawn from global platform traffic.