Large-scale AI datacenter platforms comprise thousands of heterogeneous hardware components whose validation requires comprehensive fault injection test plans. Today these plans are authored manually: engineers review hardware self-healing validation documents and bills of materials, enumerate failure modes per field-replaceable unit, and produce flat lists of single-layer test cases. This process is labor-intensive, error-prone, and dependent on institutional knowledge; coverage gaps surface late, traceability to source specifications is implicit, and the effort is largely repeated per platform. This paper presents a generative AI multi-agent architecture that automates the generation of structured hardware validation test plans from two canonical inputs: self-healing validation documents, which enumerate known failure modes and their detection and remediation behaviors per field-replaceable unit, and component Bills of Material. An ingestion agent normalizes heterogeneous inputs into a canonical representation; a classification agent maps components to functional domains via contextual reasoning over part descriptions and sub-category hierarchies; and a generation agent synthesizes test cases by combining normalized failure modes with domain-classified data, filling gaps and producing edge cases. The output conforms to a standardized schema for direct import into internal validation software. Evaluated on two production platforms against manual baselines, the framework achieves coverage expansions of 74.2% and 51.4%, cutting authoring from days to hours. It yields fully traceable mappings from each test case to its source specification, and its multi-agent decomposition is portable across platform generations. Automated and expert evaluations confirm 100% extraction fidelity and high acceptance of new scenarios, validating the framework as a robust human-in-the-loop force multiplier.
Niko Moeller-Grell, Shihao Shenzhang, Zhangshu Joshua Jiang +2cs.AI cs.MA
The Observational Medical Outcomes Partnership Common Data Model (OMOP CDM), maintained by the Observational Health Data Sciences and Informatics (OHDSI) collaboration, enabled the harmonisation of electronic health records data of nearly one billion patients in 83 countries. Yet generating real-world evidence (RWE) from these repositories remains a manual process requiring clinical, epidemiological and technical expertise. LLMs and multi-agent systems have shown promise for clinical tasks, but RWE automation exposes a fundamental challenge: agentic systems introduce emergent behaviours, coordination failures and safety risks that existing approaches fail to govern. No infrastructure exists to ensure agentic RWE generation is flexible, safe and auditable across the lifecycle. We introduce FastOMOP, an open-source multi-agent architecture that addresses this gap by separating three infrastructure layers, governance, observability and orchestration, from pluggable agent-teams. Governance is enforced at the process boundary through deterministic validation independent of agent reasoning, ensuring no compromised or hallucinating agent can bypass safety controls. Agent teams for phenotyping, study design and statistical analysis inherit these guarantees through controlled tool exposure. We validated FastOMOP using a natural-language-to-SQL agent team across three OMOP CDM datasets: synthetic data from Synthea, MIMIC-IV and a real-world NHS dataset from Lancashire Teaching Hospitals (IDRIL). FastOMOP achieved reliability scores of 0.84-0.94 with perfect adversarial and out-of-scope block rates, demonstrating process-boundary governance delivers safety guarantees independent of model choice. These results indicate that the reliability gap in RWE deployment is architectural rather than model capability, and establish FastOMOP as a governed architecture for progressive RWE automation.