Continuous physiological time series underpin modern clinical monitoring, yet many of the most informative signals are invasive, expensive, or simply unavailable for a given patient. Conditional generation offers a remedy: an absent signal can be synthesized from co-recorded signals and routine clinical variables. Existing generators, however, are built around a single conditioning modality and degrade when forced to handle the heterogeneous, irregularly missing mix of time-variant signals and static covariates seen in practice. We propose ReCoGen (Represent Conditions, then Generate), a two-stage framework that decouples multimodal condition representation from target generation. Stage I trains one masked autoencoder per modality, distilling each time-variant condition into a compact and missingness-tolerant token sequence. Stage II trains a flow-matching generator that fuses these tokens with static conditions to synthesize the target signal. Across three physiological benchmarks, including continuous glucose monitoring on AI-READI and arterial blood pressure generation on MIMIC-III and MIMIC-IV, ReCoGen attains the best downstream utility on all sixteen (dataset, task, metric) settings, surpassing six representative conditional generators; on thirteen of them its utility also reaches or exceeds the utility measured on the real signal, a reference we read as an approximate anchor rather than a ceiling. Ablations trace the gains to the conditioning path: learnable cross-attention over the frozen per-modality encoders, and a dual token-plus-AdaLN route for the static conditions. ReCoGen thus turns routinely collected signals into informative surrogates for invasive or unavailable ones, a step toward less invasive, lower-cost continuous clinical monitoring.
Estimating hand-surface contact pressure from an egocentric view is crucial for AR/VR devices, robotic imitation, and ergonomic analysis. Existing methods often discretize pressure signal and process frames independently, leading to quantization errors and temporal inconsistencies. We present \emph{EgoPressDiff}, a conditional video diffusion framework that generates UV-pressure maps from visual input. The core of our approach is a multi-modal conditioning strategy, introducing a PoseNet and a Vertex Encoder to efficiently extract features from hand pose and 3D mesh vertices. These signals, along with depth information, guide the generative process to ensure the pressure fields are physically grounded. To effectively fuse these heterogeneous features, we further propose a Distribution-Calibrated Spatial Layer, which aligns their statistical properties before combination. Evaluated on the EgoPressure ego-view setting, EgoPressDiff achieves state-of-the-art results, improving Volumetric IoU by over 34\% relative to prior baseline, while reducing MAE and maintaining high temporal accuracy. Our project page is at https://egopressdiff.github.io/.