Twoblock clustering trees with coskewness-based dimension reduction: recovering piecewise multivariate linear regimes

The twoblock clustering tree (\tbtree) is introduced as a highly interpretable regression tree for multivariate responses. Twoblock trees are deterministic decision trees that have local multivariate linear models as their leaves and use dense or sparse twoblock dimension reduction as local leaf models and in the impurity. The resulting models are both computationally efficient and can be highly interpretable. Beyond proposing the decision tree estimator itself, this paper also introduces an estimator for the twoblock dimension reduced space based on maximizing coskewness, which facilitates identification of non-normal clusters in the data. The tree inherently produces a set of local linear models and is therefore apt to recover peicewise linear regimes, which is illustrated in a simulation. However, two real world data examples illustrate that twoblock trees are also capable of modeling more complexly nonlinear dependencies and can perform on par with black box modeling techniques, such as random forests. At each point, both the twoblock models that generate the splits, as well as the ones in the leaves, can be inspected and interpreted.

Multivariate Varying-Coefficient BART with Graphical Horseshoe Priors

Modern multivariate regression problems involve several related outcomes whose regression effects are not only nonlinear, heterogeneous, and outcome-specific, but also where the residual dependence among outcomes is scientifically meaningful. Existing multivariate Bayesian tree-based methods typically address only part of this problem: some impose substantial sharing of tree architecture across outcomes, which is overly restrictive when responses depend on distinct predictors or effect modifiers, while others accommodate residual dependence but retain simpler mean structures. This paper develops multiVCBART, a multivariate varying-coefficient Bayesian additive regression tree framework that jointly models flexible outcome-specific coefficient surfaces and a sparse residual precision matrix. Each entry of the coefficient matrix $B(x)$ is represented by an independent BART ensemble, allowing predictor effects to vary nonlinearly with modifiers $x$ across outcomes, while a Graphical Horseshoe prior on the precision matrix $Ω$ captures parsimonious residual conditional dependence. To permit efficient computation, we introduce a sampler that reduces the multivariate Gaussian likelihood to a sequence of scalar pseudo-response updates, decoupling the tree backfitting from the Graphical Horseshoe step. Theoretically, we establish the first posterior contraction rates for a multivariate BART model with jointly estimated residual dependence, proving near-minimax adaptation to underlying smoothness and structural sparsity. Empirically, multiVCBART outperforms existing multivariate tree models and Bayesian SUR competitors on sparse, high-dimensional datasets. Finally, in a re-analysis of the Genomics of Drug Sensitivity in Cancer dataset, our method identifies distinct biomarker signals and recovers a coherent residual pharmacologic network.