Jieyu Zhang, Ziqi Gao, Luke Zettlemoyer +1cs.CV cs.AI cs.CL
Vision-language grounding connects language to visual content, yet most existing formulations reduce grounding to a unidirectional localization problem: given a prespecified text phrase or category name, identify the corresponding image region. This setup assumes that the relevant linguistic unit is already known, overlooking a more basic challenge in grounded communication: determining which parts of the text are visually referential and how they correspond to entities in the image. We formulate grounding as $\textit{bidirectional concept correspondence}$ over an image-text pair. Given an image and its paired text, the goal is to recover all correspondences between visually referential text spans and instance-level image segments, without assuming that the relevant text spans are provided. This formulation unifies common grounding tasks, including phrase grounding, referring expression grounding, and open-vocabulary detection, by treating text segmentation, image segmentation, and cross-modal alignment as a single correspondence prediction problem. To address this task, we introduce $\textbf{ConCor-1}$, a grounding model built on top of a pretrained vision-language model. It uses learnable $\textit{bridge tokens}$ to represent candidate image-text correspondences and predicts, for each token, a text mask, an image mask, and a correspondence presence score. To train and evaluate this task, we convert diverse grounding and segmentation datasets into a unified correspondence format. Experiments show that $\textbf{ConCor-1}$ consistently outperforms baselines, improving correspondence F1 by 48% on the long-caption dataset and by 29% on zero-shot LVIS, where the large category list serves as the text input.
Fine-grained visual representations are essential for medical image analysis, particularly when diagnostically relevant evidence is subtle and spatially localized. Modern transformer-based medical vision encoders must therefore learn patch-level representations that are both clinically meaningful and spatially consistent. Without these properties, large vision-language models (LVLMs) operate on an ambiguous visual foundation, limiting their ability to generate clinically reliable and spatially grounded responses. However, existing training strategies for medical vision encoders rarely achieve both objectives. Image-text alignment provides clinically meaningful supervision primarily at the image level, leaving the spatial localization of diagnostic evidence weakly constrained. In contrast, self-supervised learning promotes spatial consistency but lacks the semantic supervision needed to distinguish visually similar yet clinically distinct regions. To address this gap, we present LoFi, a medical vision foundation model built on location-aware fine-grained representation learning. LoFi trains a vision encoder with a lightweight large language model under grounding and grounded captioning objectives. Because these objectives require predicting location from clinical text and vice versa, spatial consistency emerges without any explicit patch-level regularization. To enable training at scale, we construct MedG, a large-scale medical grounding dataset of 4.48M image-text-box triplets curated from 84 datasets spanning 7 modalities. Across phrase grounding, visual question answering, and region-based organ classification under perturbations, LoFi consistently outperforms general-purpose and medical vision foundation models as well as state-of-the-art LVLMs. Code is available at https://github.com/myeongkyunkang/lofi-medg.