AutoQuREO: A Framework for Automated Quantum Resource Estimation and Optimization

As quantum computing progresses from proof-of-principle demonstrations toward practical utility, a significant impediment is the need to augment algorithmic feasibility with system-level optimization across heterogeneous hardware and software stacks. Quantum resource estimation (QRE) plays a central role in this transition, yet existing approaches remain largely compilation-heavy or domain-knowledge-guided symbolic annotations, and tightly coupled to long-term fault-tolerant assumptions, limiting their topical applicability. In this work, we introduce AutoQuREO, an Automated framework for full-stack Quantum Resource Estimation and Optimization. AutoQuREO is built around four core novelties: (i) a flexible, user-defined abstraction of the quantum computing stack; (ii) a modular library of reusable stack components enabling rapid full-stack prototyping; (iii) surrogate modeling of layer-wise resources via algorithmic profiling and neuro-symbolic learning; and (iv) integrated multi-objective optimization that embeds QRE directly into deployment pipelines. Together, these design choices enable AutoQuREO to serve as a digital twin for quantum computing stacks, supporting the tractable exploration of complex design spaces. We demonstrate the capabilities of AutoQuREO through representative co-design case studies, including early-fault-tolerant quantum algorithms, small error correction codes, gate decomposition and variational training of parametric quantum circuits. These examples illustrate how AutoQuREO enables systematic discovery of unexploited resource trade-offs that are computationally intractable or abstruse using existing QRE tools. AutoQuREO is positioned as a general-purpose platform for advancing quantum technology readiness.

Think Before You Grid-Search: Floor-First Triage for LLM Serving

LLM serving optimization typically benchmarks many configurations and reaches for heavy profilers when latency targets are missed. We argue for the reverse discipline: estimation is the analytical layer of profiling -- without it, optimization degenerates to grid search. Floor First is a residual-driven triage workflow. Each decode step is modeled as a five-dimensional resource vector (HBM bytes, FLOPs, network bytes, network messages, KV capacity); summing within a resource and maximizing across resources gives an optimistic floor, the plain sum a pessimistic one. Where a measurement lands inside this [max, sum] interval reads out overlap quality before any profiler is opened, and profilers escalate only on residuals above a stated threshold. Deployment alternatives are compared by wall ordering -- which resource wall binds first as load grows -- rather than by point benchmarks. The account is compositional: new attention or state-space variants enter by declaring one module, and the workflow ships as a zero-dependency calculator plus an agent skill that enforces the discipline in agentic optimization loops. As a case study we analyze a DeepSeek-V3.2-style 671B MoE/MLA model on 16 NVIDIA H20 GPUs, whose ridge point of ~74 FLOP/byte (vs ~590 for H100) makes it an extreme decode-oriented part. The floors show TP16 decoding is KV-capacity-limited to ~70 concurrent 8K requests; sparse attention removes the KV-bandwidth term but not the capacity wall; an EP16+DP-attention layout accepts slightly worse same-batch weight traffic for an order-of-magnitude higher capacity wall (~644) -- while single-stream latency favors TP by 2.4x. The layout judgment is thus a computable function of the operating point, explaining why production deployments on identical hardware have shipped opposite attention layouts.