Bayesian-Optimized Superpixel-GrabCut for Traceable Optic Disc Segmentation

Optic disc (OD) segmentation is essential for diagnosing ophthalmic pathologies from retinal fundus images. However, prevailing deep learning approaches operate as opaque black boxes, lacking the inference-stage mathematical traceability--a critical requirement for algorithmic auditing and failure analysis in clinical workflows. This paper presents a fully algorithmically traceable and trainable segmentation pipeline that jointly combines superpixel decomposition, hybrid brightness-proximity superpixel scoring, morphological regularization, iterative GrabCut refinement, and elliptical shape fitting. The hyperparameter optimization is formulated as an objective function and solved via Bayesian optimization to eliminate manual parameter tuning. A quantitative evaluation on the Drishti-GS dataset demonstrates that our method achieves a Dice coefficient of 0.9536, matching state-of-the-art performance. By maintaining explicit mathematical transparency across all processing stages, our framework offers a deterministic, traceable alternative to black-box architectures for medical review and debugging.

Braided Vision Transformer for Stroke Detection in Multi-view Retinal Fundus Imaging

Stroke remains a leading cause of mortality and morbidity worldwide, emphasizing the importance of its accurate and immediate assessment. Retinal fundus imaging has emerged as a promising modality for stroke assessment, as the retina reflects cerebrovascular and neurological risk factors. Contrary to conventional neuroimaging techniques, retinal fundus imaging offers a non-invasive, cost-effective, and portable alternative for rapid screening. This paper explores the feasibility of retinal fundus imaging for stroke and transient ischemic attack (TIA) detection using macula-centric and optic nerve head-centric views captured from both eyes. Our study introduces, to the best of our knowledge, the first vision transformer model for retinal fundus imaging in stroke assessment, offering a novel approach for capturing retinal patterns. Thereby, we propose the Braided Vision Transformer (BViT) model, which extracts representative features from the given multi-view images while simultaneously capturing inter-view relationships across both eyes, enabling a more informative understanding of retinal biomarkers associated with cerebrovascular events. Experiments conducted on our collected Stroke-Data dataset demonstrate that BViT achieves an AUC score of 0.75 for stroke detection, outperforming regular vision transformers.