Scientific exploration, collaboration and labor division in the large language model era

Large language models (LLMs) have rapidly and significantly entered scientific workflows, but it remains unclear how their diffusion is associated with changes in scientists' strategies in research directions and team building. We link PubMed Central full text with OpenAlex publication and collaboration histories for 775,323 scientists and analyze CRediT contribution statements from 137,120 multi-author papers. After 2022, scientists increasingly published across more intellectually distant fields and entered fields in which they had not previously worked. These increases in interdisciplinarity and exploration were especially pronounced among established scientists and scientists from non-English-speaking low- and middle-income countries. Authors with stronger AI-writing signals were already more interdisciplinary and exploratory before the widespread adoption of LLMs, and the gap widened further after 2022 compared with authors with weaker AI-writing signals. Scientists' collaboration networks also became more interdisciplinary after 2022. Yet, among authors with stronger AI-writing signals, research interdisciplinarity was less closely tied to the disciplinary diversity of their collaborators. The division of labor within research teams also became more differentiated. Contributors on papers published after 2022 reported narrower role sets on average, coauthors shared fewer roles in common, and their role profiles became less rigid and more fluid. Software and validation roles increased, while conceptual and management roles decreased. These patterns suggest that team members are taking on more distinct responsibilities and may rely less on one another to perform research tasks. Overall, this study indicates that the LLM era coincides with a broader reorganization of scientific exploration, collaboration, and the division of labor.

CoWeaver: A Bi-directional, Learnable and Explainable Matching Engine for Mixed Human-Agent Science Collaboration

LLM-based agents excel at writing articles, coding and information retrieval. However, they fail to form strong collaborations within the scientific community due to the bidirectional, dynamic nature of the problem and a high demand of decision interpretability. We proposed COWEAVER, a bidirectional, learnable and explainable algorithm to match scientists and form strong collaborations within a human-agent network. COWEAVER matches candidates and requesters through filling capability gaps and filters candidates through a two-stage ranking step. Finally, the model explores newcomers by maintaining uncertainty-aware capability estimates and updating them through requester's feedback. We show that the selection mechanism of combining both exploration (UCB) and greedy of COWEAVER exceeds the greedy-only mechanism - the analytical best solution - on 6 out of the 20 tasks and performed on par with the greedy-only mechanism in terms of selecting the best candidate. We compared COWEAVER baselines in terms of matching quality and efficiency. COWEAVER outperforms baselines on all metrics.

Archi: Agentic Operations at the CMS Experiment

We present Archi, an open-source, end-to-end framework for scientific collaborations that combines the systematic ingestion and organization of heterogeneous data sources with the deployment of configurable, private, and extensible agents that retrieve and reason over them. An instance of Archi has been deployed for the Computing Operations team of the CMS experiment at CERN's LHC since February 2026 as a support agent for technical operators, offering retrieval and analysis capabilities by combining documentation, historical data, and live monitoring systems. We evaluate the system on operator feedback and a question set collected from production usage, graded by human and automated panels. The system proves effective at operational tasks, resolving real-world queries posed by CMS operators. We also observe that locally-hosted, open-weight models perform competitively, enabling fully private management of sensitive data.