The perception-distortion trade-off poses a fundamental challenge in single-image super-resolution (SR). Although diffusion-based SR methods excel at generating perceptually realistic images, achieving high fidelity remains a key limitation. Recent advances in diffusion-based SR have shown promise in improving fidelity, but these methods often compromise perceptual quality due to their high reliance on a high-fidelity image. To address this, we introduce UGDiff, a novel diffusion guidance paradigm designed to further improve the perception-distortion balance. In particular, we first estimate the reconstruction uncertainty of the latent features corresponding to a high-fidelity image. This uncertainty is then used to guide the diffusion process to selectively restore high-frequency details in high-uncertainty regions, while preserving fidelity elsewhere. Furthermore, our guidance method adaptively identifies the high-uncertainty regions by considering not only the estimated uncertainty but also the posterior variance of the diffusion sampler at each timestep. This relaxes the reliance on the high-fidelity image in the later stages of sampling, thereby achieving a better perception-distortion balance. Extensive experimental results demonstrate that our method performs favorably against state-of-the-art diffusion-based SR methods.
Duong M. Nguyen, Tuan Nghia Nguyen, Xuan Truong Nguyencs.CV cs.AI eess.IV
To accelerate single image super-resolution (SISR) networks on large images (2K-8K), many recent approaches decompose an image into small patches and dynamically determine an execution path according to its difficulty (referred to as a dynamic network). To quantify the hardness of a patch, they mainly rely on a handcrafted assessment score, e.g., edge, which weakly associates a patch's texture with the computational complexity of a SISR model. To address the problem, we introduce ENAF - a dynamic network for SISR with an adaptive patch fusion. Built on top of a backbone, ENAF incorporates multiple early exits (EEs) to tackle the over-parameterized SISR model. More importantly, ENAF plugs a tiny network that estimates PSNR to associate data texture with a computation cost at an EE. Based on the scores, ENAF effectively assigns image patches to an exit, enhancing the quality-complexity trade-off. Extensive experiments on common datasets with popular SISR backbones demonstrate the effectiveness of ENAF in various settings. The source code is provided in https://github.com/nmduonggg/ENAF
Digital pathology relies on high-resolution whole slide images for accurate diagnosis, yet limitations in imaging devices, storage, and transmission often make lower-resolution pathology images more common in clinical workflows. Current super-resolution techniques often tend to smooth diagnostically relevant morphology, leading to over-smoothed textures and semantic drift that compromise downstream clinical interpretation. To this end, we develop the Structural Semantic Synergy Diffusion Model (S3-Diff), a diffusion framework for high-fidelity super-resolution of pathological images. The core of S3-Diff is Specimen-aware Structural Anchoring (SSA), which combines prognosis-aware tissue support extracted by a fixed SAM with LR-HR gradient discrepancies to generate a specimen-specific structural anchor to preserve pathological morphology. Concurrently, we introduce Structure-guided Semantic Fidelity Tuning (SSFT) to adapt DINOv3 representations using SSA-derived structural supervision. SSFT combines the adapted semantic energy with LR-derived edge and grayscale cues. The resulting control guides denoising to suppress stochastic artifacts and maintain structural consistency. Extensive experimental results demonstrate that S3-Diff consistently outperforms state-of-the-art methods in both reconstruction quality and downstream survival analysis performance. The source code will be made public.