THBKG: A Temporal Biomedical Knowledge Graph for Decision-Aligned Clinical Advancement Prediction

Inadequate target--disease linkage accounts for 40--50\% of Phase~II efficacy failures, so anticipating which programmes will advance would let sponsors back the hypotheses most likely to reach patients. What a programme can be judged on is the evidence that supported its linkage \emph{when it entered the clinic}. No existing biomedical knowledge graph allows that evidence profile to be assembled as of a past date. We present the Temporal Heterogeneous Biomedical Knowledge Graph (THBKG), which describes and predicts therapeutic target--disease links through time: 110,396 entities and 11.1M edges across nineteen relation types, each edge carrying the year its evidence changed, so a pair's profile can be recovered as it stood when its own decision fell due. On this graph we define a decision-aligned benchmark that predicts, for a target--disease pair entering Phase~II, whether it advances to Phase~III on evidence datable before that decision. Graph propagation over the THBKG outranks every direct-evidence reference scored under the same decision-aligned protocol, reaching a relative success of 4.3--4.5 at the top ten pairs per therapeutic area. The gain concentrates on the 72.8\% of pairs with no direct target--disease evidence at their decision point, where a direct-edge model has nothing to read: the encoders still rank five- to sixfold above chance, recovering the signal by propagating over the intervening biology. Adapting a path-based explainer to the decision-time subgraph decomposes each prediction into the evidence landscape behind the hypothesis for explainable prediction. We release the THBKG as a continually updated substrate for studying therapeutic target hypotheses by retrospective validation.

Narrative World Model: Narratology-Grounded Writer Memory for Long-Form Fiction

Long-form fiction writers need memory that answers multi-hop questions about evolving story state: who knows a secret and when they learned it, whether an event preceded the narration that revealed it, whether a setup paid off, and how a relationship shifted. General-purpose retrieval and agent-memory systems represent entities and facts but not the narratological structure these questions turn on, so they surface the wrong evidence or none at all. We introduce the Narrative World Model (NWM), a writer-memory system that pairs a narratology-grounded typed temporal-state graph with query-conditioned hybrid retrieval. To measure memory rather than the answerer, we read every system through a single held-constant Opus 4.8 reader over only that system's chapter-safe evidence, on a reproducible public corpus and a validated multi-hop benchmark, and we compare against the strongest existing temporal-knowledge-graph agent-memory framework, Graphiti/Zep (Rasmussen et al., 2025). NWM substantially and significantly outperforms this baseline on multi-hop narratological QA across both corpora, and far exceeds GraphRAG and flat retrieval. The advantage is representational rather than an artifact of extraction: it survives rebuilding the baseline with NWM's own extractor, and traces to its narratology-grounded structure and query-conditioned retrieval, not to graph size or extractor quality.

PulseCX: Breaking the Closed-World Assumption in Real-Time CX

Conversational AI agents in Customer Experience (CX) typically suffer from a Closed-World Constraint, ignoring high-velocity external shifts like viral trends or outages. Ad-hoc web search attempts to bridge this gap but often introduce prohibitive latency and context poisoning. We introduce PulseCX, a framework that decouples knowledge acquisition from consumption. Adopting a structure-first paradigm, PulseCX employs an asynchronous agent to linearize signals into a Decay-Aware Temporal Knowledge Graph (DA-TKG) governed by reinforcement--decay dynamics to actively manage information lifecycles. By coupling this self-evolving memory with hierarchical intent gating, PulseCX removes synchronous search bottlenecks (<10ms overhead) and drives significant gains in Intent Resolution (IRR) and Customer Satisfaction (s-CSAT) in dynamic environments.

DYNA : Dynamic Episodic Memory Networks for Augmenting Large Language Models with Temporal Knowledge Graphs in Continuous Learning

Large Language Models (LLMs) struggle to incorporate new knowledge without forgetting or costly retraining. We propose DYNA, a lightweight framework that augments a frozen LLM with a temporal knowledge graph where events are nodes and temporal relations are directed, timestamped edges. The graph serves as an external, updatable memory. At query time, DYNA retrieves relevant nodes via random walks and centrality measures, then augments the LLM's response. Evaluated on three temporal recall tasks, DYNA reduces catastrophic forgetting by ~7% compared to fine-tuning and improves temporal ordering by ~5% over standard RAG. Higher graph clustering coefficients correlate with better retrieval, showing that graph structure matters. Contributions: (1) episodic memory as temporal KG, (2) retraining-free LLM augmentation, (3) graph properties as predictors of retrieval performance.

CHE-TKG: Collaborative Historical Evidence and Evolutionary Dynamics Learning for Temporal Knowledge Graph Reasoning

Temporal knowledge graph (TKG) reasoning aims to predict future events from historical facts. A key challenge lies in jointly capturing two sources of predictive information in TKGs: historical evidence and evolutionary dynamics. However, existing methods typically focus on only one of these sources, which limits the ability to fully exploit the complementary predictive signals in TKGs. To address this, we propose CHE-TKG, a novel collaborative dual-view learning framework for TKG reasoning. CHE-TKG explicitly separates and jointly models historical evidence and evolutionary dynamics, aiming to learn and exploit their complementary predictive signals. Specifically, CHE-TKG constructs a historical evidence graph to capture long-term structural regularities and stable relational constraints, alongside an evolutionary dynamics graph to model temporal transitions and recent changes, with dedicated encoders for each view. We further employ relation decomposition and a contrastive alignment objective to better capture the predictive signals across the two views. Extensive experiments demonstrate that CHE-TKG achieves state-of-the-art performance on multiple benchmarks.