Xiaohan Zhang, Sebastian Starke, Alexander Winkler +3cs.CV
Synthesizing realistic full-body human interactions with articulated objects is a fundamental challenge for embodied AI and graphics, with applications in robotics training and virtual agents. Existing models remain limited: some focus on simple activities with static objects, while others restrict attention to hand-only manipulation. This leaves open the problem of generating coordinated full-body motion that approaches, manipulates, and moves articulated objects in a realistic and generalizable way. The key difficulty lies in reasoning jointly about locomotion, fine-grained contact, and object articulation. Models must capture subtle hand-object correspondences that transfer across object geometries, while also producing seamless transitions from navigation to manipulation. At the same time, the scarcity of large-scale paired motion-scene data makes it difficult to generalize across diverse object positions and shapes. We introduce a text-conditioned diffusion model that addresses these challenges through three core ideas: an object-centric representation that unifies hand-object contact with object surfaces, a mixed-domain training strategy that balances locomotion and interaction, and a contact-based augmentation scheme that expands training diversity. Through experiments, our method demonstrated strong generalization to unseen object configurations, surpassing current state-of-the-art methods.
Text-conditioned human interaction generation must capture both long-range temporal causality within each individual and tightly coupled coordination between partners. Existing interaction diffusion models typically denoise full sequences using bidirectional attention, which obscures causality and hinders streaming and long-horizon generation. Autoregressive alternatives enforce causality but often suffer from temporal drift, leading to coordination degradation and unstable interaction dynamics over time. We propose InterCMDM, a block-causal latent diffusion framework for autoregressive two-person interaction generation. InterCMDM introduces a Dual-Stream Causal Diffusion Transformer that maintains separate causal streams for each person while modeling inter-person dependencies via unified dual-stream attention with multi-task attention masks. These masks unify interaction modeling within a single attention mechanism and support diverse coordination behaviors, including simultaneous actions, reactive responses, leader-follower dynamics, and independent motion. By training a single model across these mask configurations as a form of data augmentation, InterCMDM enables controllable interaction generation by simply selecting the desired attention mask at inference time. Finally, a block-wise diffusion objective enables stable latent rollout over long sequences without repeated decode-encode cycles. InterCMDM achieves state-of-the-art performance on InterHuman and Inter-X, improving text-motion alignment, realism, and long-horizon continuity.
Francesca Pia Panaccione, Eugenio Lomurno, Francesca Fati +11cs.CV cs.AI cs.LG
Ovarian cancer is frequently diagnosed at an advanced stage, making preoperative contrast-enhanced computed tomography (CT) central to staging and surgical planning; yet the scarcity of annotated imaging data, compounded by privacy regulations, limits the development of generalizable computational models in this domain. Text-conditioned 3D CT synthesis has shown promise, but existing pipelines depend on paired radiology reports and have been evaluated only on chest CT. We propose OvESyn (Ovarian Evidence-based Synthesis), a framework that constructs standardized Findings and Impression sections directly from CT-derived imaging descriptors and routine clinical metadata, without any original radiology report, and uses them to condition a latent diffusion model adapted to 493 high-grade serous ovarian carcinoma patients. This is the first text-conditioned 3D CT synthesis framework adapted to an abdomino-pelvic oncologic setting. A systematic ablation over two adaptation axes, vision-language encoder alignment and generator fine-tuning, identifies generator domain adaptation as the operative mechanism for crossing the domain gap and establishing the target anatomy: without it, synthesis remains anchored to the thoracic pretraining domain, with Precision and Recall collapsing to zero and FID2.5D exceeding 140, regardless of encoder alignment. Encoder alignment instead refines intensity and fine detail. The full OvESyn attains the best distributional and intensity fidelity (FID2.5D 29.35, Precision 0.671, Wasserstein-1 0.044), while the generator-only variant maximizes coverage (Recall 0.645), reflecting a fidelity/coverage trade-off governed by encoder adaptation. Requiring only automatic segmentations and routine preoperative metadata, OvESyn supports transferability to report-scarce settings and provides a foundation for synthetic cohort generation in abdomino-pelvic oncologic imaging.
Modeling 4D human-object interaction (HOI) is a compelling challenge in computer vision and an essential technology powering virtual and mixed-reality applications. While existing works have achieved promising results on specific HOI tasks-such as text-conditioned HOI generation and human motion generation from object motion, they typically rely on task-specific architectures and lack a unified framework capable of handling diverse conditional inputs. Building on this, we propose Uni-HOI, a unified framework that learns the joint distribution among text, human motion, and object motion. By leveraging large language models (LLMs) and two motion-specific vector quantized variational autoencoders (VQ-VAEs), we convert heterogeneous motion data into token sequences compatible with LLM inputs, enabling seamless integration and joint modeling of all three modalities. We introduce a two-stage training strategy: the first stage performs multi-task learning on a large-scale HOI dataset to capture the underlying correlations among the three modalities, while the second stage fine-tunes the model on specific tasks to further enhance performance. Extensive experiments demonstrate that Uni-HOI achieves remarkable performances on multiple HOI-related tasks including text-driven HOI generation, object motion-driven human motion generation (optionally with text) and human motion-driven object motion prediction within a unified framework.
Bridging molecular structures and natural language is essential for controllable design. Autoregressive models struggle with long-range dependencies, while standard diffusion processes apply uniform corruption across positions, which can distort structurally informative tokens. We present BiMol-Diff, a unified diffusion framework for the paired tasks of text-conditioned molecule generation and molecule captioning. Our key component is a token-aware noise schedule that assigns position-dependent corruption based on token recovery difficulty, preserving harder-to-recover substructures during the forward process. On ChEBI-20 and M3-20M, BiMol-Diff improves molecule reconstruction with a 15.4% relative gain in Exact Match and achieves strong captioning results, attaining best BLEU and BERTScore among compared baselines. These results indicate token-aware noising improves fidelity in molecular structure-language modelling.