Calibrating a superconducting transmon chip is a sequential decision problem under noise, drift, and a finite budget: an expert must choose experiments, read ambiguous plots, judge fit quality, and revise stale beliefs as the chip drifts. We study whether a vision-language agent can close this loop and specialize itself to one physical device without weight updates, via three co-designed artifacts. The first is a physics-grounded simulation environment for transmon chips: calibration observables derive from circuit-quantized parameters via scqubits, with realistic flux-line distortion, wall-time-scaled and mid-scan drift, and gate leakage, concerns a toy simulator would omit; each tool call advances a modeled clock so drift accrues by wall time, not call count. The second is a vision-language agent that runs the loop end to end, calling tools, reading plots, maintaining a structured notebook, and submitting parameters without hidden truth, scored against hidden parameters and gate fidelities measured on the device. The third is gradient-free online adaptation: a reflector reads truth-free anomaly signatures from past attempts and grows a small, human-readable device note appended to the prompt, admitted by a paired-snapshot accept gate that isolates strategy improvement from drift. On a hard-tier chip under budget pressure, six iterations raised the worst-case CZ fidelity from 0.678 to 0.787 and cut its variance, reproducing at four-qubit scale; a single accepted note raised CZ fidelity from 0.678 to 0.913 on its paired snapshot. A planted-fault study confirms the note is causal, diagnosing a hardware fault truth-free, its principal value raising the failure floor and cutting variance. The agent, scoring, and reward transfer to real hardware via a measurement-backend swap; only the accept gate is a simulation affordance, reducing to a held-out-slice or repeat-and-average form.
Imperfectly supervised video polyp segmentation (VPS) aims to learn dense, temporally consistent masks from inexpensive supervision, including weak annotations (points, scribbles) and semi-supervision with few densely labeled frames. This setting is clinically valuable but challenging due to weak contrast, ambiguous boundaries, motion blur, and specular highlights, compounded by sparse pixel-level guidance. While SAM2 can generate dense masks from sparse inputs, direct pseudo-labeling often yields geometry-degraded masks with boundary leakage, underutilizes temporal consistency, and ignores reliability. To address these issues, we propose ARTEMIS, a unified framework for imperfectly supervised VPS driven by agent-guided reliability-aware temporal mask evolution. ARTEMIS initializes coarse masks from available supervision: SAM2 converts points/scribbles, while dense labels serve as reliable anchors. A debate-and-judge vision-language agent selects reliable temporal anchors under weak supervision, which are propagated bidirectionally with SAM2 to refine unreliable or unlabeled frames. Finally, ARTEMIS trains the segmenter using temporal reliability-aware robust learning, incorporating reliability-guided reference selection, a Reference Prototype Transport Module, and reliability-aware robust loss. These components assess mask reliability, evolve anchors over time, transport target identity across frames, and down-weight noisy supervision instead of discarding difficult samples. Experiments on SUN-SEG and CVC-ClinicDB-612 under scribble, point, and limited-label settings demonstrate that ARTEMIS achieves state-of-the-art performance. Code will be released at https://github.com/wangtong627/ARTEMIS.