The Past and Future of AI Scientists
Ross D. King
Abstract
We present a survey of the past and future of AI Scientists: machines capable of automating science. AI Scientists can originate hypotheses, deduce their consequences, design and execute experiments, interpret their results, and revise their beliefs. Such systems are integrated scientific agents, connected to the literature, formal knowledge, mathematical models, simulations, data-analysis systems and physical laboratories. Adam was the first machine to make novel scientific discoveries through cycles of hypothesis formation and physical experimentation. Eve established the architecture of the modern self-driving laboratory. Foundation models, autonomous agents and laboratory robotics now make it possible to build systems far more general than either Adam or Eve. The central problem is no longer whether individual components of science can be automated. They can. The problem is integration. AI Scientists must combine neural learning with logic, probability, mathematics, causal reasoning, simulation, experimental design, robotics and formal scientific records. AI Scientists have the potential to transform science: to make science faster, cheaper, more systematic and more reproducible. AI Scientists could investigate systems too complicated for unaided human science, and enable thousands of AI scientists to work together on single problems. The Nobel Turing Challenge sets the goal of developing by 2050 AI systems capable of automating Nobel-quality discoveries. Progress is ahead of schedule. When we succeed it will create a new form of science and transform the world.
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Classified with taxonomy v2 on Sat, 5 Sept 2026.