The joint interpretation of metabolic function and anatomical structure is essential for clinical diagnosis in whole-body PET/CT. Although recent advances in 3D medical vision-language models have demonstrated remarkable progress, current efforts are limited to regional CT imaging, leaving a critical void in comprehensive whole-body PET/CT analysis. In this work, we introduce MetaStructAtlas, a large-scale dataset for grounded whole-body PET/CT interpretation that synthesizes multimodal imaging with integrated anatomical, metabolic, and semantic annotations. MetaStructAtlas provides 490 co-registered 3D PET and CT volumes with 50,470 organ-level segmentation masks and grounded radiology reports. To facilitate interactive reasoning, we further developed MetaStructVQA, a standardized 3D grounded visual question-answering benchmark containing 100,565 QA pairs. This framework explicitly links diagnostic queries to visual evidence across modalities, encompassing anatomical, morphological, and metabolic characteristics. Finally, we evaluate state-of-the-art 3D medical VLMs on MetaStructVQA, establishing a robust foundation for multimodal representation learning and integrated whole-body reasoning in nuclear medicine.
Kit M. Bransby, Esther Øksnebjerg, Kristoffer Kjær +7cs.CV cs.AI
Accurate segmentation of the coronary vessel lumen is a prerequisite for quantitative assessment of atherosclerotic plaque and perivascular adipose tissue in coronary computed tomography angiography (CCTA). Cardiologists rely on semi-automated methods for this task because manual vessel tracing and segmentation are labour-intensive. Although many automated methods have been proposed, their validation remains limited by the lack of large, high-quality publicly available datasets. We provide a new dataset of voxel-wise annotations of the vessel lumen and coronary segments, alongside centerlines, and mesh surfaces for 800 scans from the publicly available ImageCAS dataset. Using this dataset, we benchmark established lumen segmentation methods against inter-observer variability, stratifying performance by disease, image quality, coronary dominance, coronary segment, vessel diameter, and lumen attenuation. These labels allow segmentation accuracy to be described in anatomical and clinical context rather than reported as a single aggregate score. The dataset supports the development and validation of methods for lumen segmentation, plaque and perivascular quantification, and haemodynamic modelling.
Malaria remains a significant global health burden, necessitating continuous research efforts to understand its complex molecular mechanisms, epidemiology, and potential therapeutic interventions. Extracting essential biomedical information from the vast and constantly growing malaria literature is a challenging task that demands innovative approaches. Recently, pre-trained language models have revolutionized natural language processing tasks, demonstrating remarkable capabilities in various domains. This paper proposes a fine-tuned pre-trained biomedical language model for biomedical information extraction from scientific literature on malaria disease. The proposed methodology selects and preprocesses a large corpus of scientific articles on malaria, and then annotates them with entities of clinical significance. It then leverages BioBERT, a state-of-the-art pre-trained language model, to encode the textual data into context-aware representations. We fine-tune the model using domain-specific annotations and supervised learning to enhance its ability to extract relevant biomedical named entities. Extensive experiments and comparisons with different encoding and machine learning algorithms show that the proposed approach significantly outperforms them in precision, recall, and accuracy. We also publish our human-labeled dataset for entity and relation extraction to enable other health informatics researchers to train advanced models for malaria information extraction.
Anik Saha, Fahmida Sultana Naznin, Sadatul Islam Sadi +3cs.CL
Reliable medical conversational AI requires authentic expert--patient interaction data, yet such datasets remain scarce, especially for low-resource languages such as Bengali. We present DocTalkBN, a large-scale multimodal dataset of real-world expert telemedicine conversations in Bengali, collected from nationally broadcast telemedicine programs featuring board-certified physicians. DocTalkBN contains 557.63 hours of paired audio and text, 1,515 multi-turn patient calls, 10,274 host--doctor question--answer exchanges, totaling 1.7M tokens, spanning 26 medical specialties. Unlike prior resources derived from medical forums, written health content, or synthetic data, our dataset preserves the spontaneity, contextual richness, and spoken characteristics of authentic medical interactions in a low-resource setting. To support benchmark-driven research, we further construct three downstream tasks from the corpus, medical triage classification, advice safety evaluation, and medical named entity recognition, and benchmark a diverse set of large language models and encoder-based baselines. Our results show that DocTalkBN is a practically useful resource, particularly for clinically grounded reasoning tasks. We release this resource to facilitate future research on reliable medical NLP and safer, more culturally grounded healthcare systems for low-resource languages. Our source codes and dataset are publicly available at https://anonymous.4open.science/r/doctalk.
Karen Sanchez, Carlos Hinojosa, Albert A. Ávila +5cs.CV
Quantifying wound tissue composition is essential for monitoring chronic ulcer progression and guiding treatment decisions. However, pixel-level annotations are costly, and multi-tissue wound datasets remain scarce, particularly for neglected diseases such as leprosy. We introduce LUTSeg, a longitudinal chronic ulcer dataset comprising 141 images from 39 patients with wound masks and five tissue categories annotated by five expert clinicians, including a multi-expert gold-standard subset for inter-rater agreement analysis. To establish an initial benchmark for LUTSeg, we further propose TiSage, a semi-supervised tissue segmentation framework that integrates multi-scale semantic priors from a frozen medical vision-language model within a teacher-student architecture. We evaluate TiSage on LUTSeg and DFUTissue, showing improvements over supervised and semi-supervised baselines in most low-label settings. Code & data: https://github.com/carlosh93/TiSage
Francesco Mantegna, Dulhan Jayalath, Gereon Elvers +12cs.LG cs.CL
We introduce LibriBrain100, a large-scale MEG dataset for speech decoding designed from the ground up for reproducible, standardised evaluation. LibriBrain100 more than doubles the size of the original LibriBrain release, resulting in over 100 hours of high-quality MEG acquired while subjects listened to naturalistic continuous speech. With $\sim$80 hours from a single subject, LibriBrain100 sets a new record for deep, within-subject neural data (8$\times$ more than the next comparable dataset and roughly 80$\times$ more than other datasets). To demonstrate the payoff of this depth-first design, we evaluate on a word-classification benchmark---an increasingly well-established stepping stone towards the open challenge of noninvasive brain-to-text decoding. Using an existing decoding model, we achieve state-of-the-art performance---validating both the quality of the recordings and the value of within-subject data at scale. Because collecting 80 hours of data per user is impractical for real-world applications, we also collected $\sim$40 minutes of additional data from each of 32 subjects. Using the same word-classification benchmark, we demonstrate the value of broad multi-subject data: supervised finetuning of a pre-trained model can substantially compensate for limited per-subject data. We provide standard train, validation, and test splits, all reproducible through an open-sourced Python library that supports easy downloading, optional preprocessing, and data loading for common deep learning frameworks. In addition, the dataset and evaluation infrastructure are being released alongside an open machine-learning competition with a public leaderboard for standardised benchmarking. Ultimately, our hope is that LibriBrain100 will accelerate progress towards practical non-invasive brain-computer interfaces, capable of restoring communication to people living with severe paralysis.
Pia Chouayfati, Alexander M. Fichtl, Miriam Anschütz +2cs.CL
Clinical diagnosis is fundamentally interactive and incremental, yet the dominant paradigm for evaluating Large Language Models (LLMs) in medicine remains static QA benchmarks or template-based dialogues. These benchmarks say little about whether a model can serve as a diagnostic agent in a dynamic clinical encounter, with LLMs showing significant accuracy and reliability degradation in multi-turn settings. To address this issue, we present MTDiag, a large multi-turn diagnostic dialogue dataset constructed from three heterogeneous sources: DDXPlus, MIMIC-IV, and published case reports (AJCR), covering common ED presentations as well as long-tail rare and atypical conditions. All cases are normalized into a canonical schema anchored in the most comprehensive and widely-adopted medical knowledge bases (UMLS concept identifiers, with ICD-10 diagnosis codes). We release the schema, a UserLM-8B-based utterance-generation pipeline, and the physician-validated dataset that converts structured clinical evidence into natural-language utterances. Importantly, we introduce and motivate clinical knowledge-grounded metrics for evaluating LLMs as diagnostic agents, beyond diagnostic accuracy, for the task of multi-turn differential diagnosis.
Healthcare documentation in the neonatal intensive care unit (NICU) presents significant challenges, with nurses spending approximately 25\% of their time on record-keeping, while up to 60\% of interventions remain undocumented. Motivated by the need to detect interventions from video automatically, we present the Infant Care Video Dataset (ICVD), a collection of 4,144 videos spanning 12 simulated intervention classes designed for developing automated documentation systems. Our manikin-based approach systematically varies conditions, such as camera angle and clinician skin tone, while ensuring privacy compliance. Using video transformer architectures (TimeSformer and MotionFormer), we establish strong baseline performance (93.97\% and 93.17\% top-1 accuracy) among the 12 infant care classes. Our ablation study comparing temporal models with a framewise approach (23.17\% accuracy) demonstrates a 70.80\% performance gap, validating the need for temporal modeling. The ICVD provides a foundation for developing automated documentation systems to reduce clinical burden in neonatal care environments and improve existing practices.
Alexandre G. Leclercq, Noémie N. Moreau, Hugo Audebert +21cs.CV
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a median overall survival of 15 months. Longitudinal, multi-modal imaging datasets with comprehensive clinical and treatment data are essential to support the development of reproducible computational methods for treatment response prediction, disease progression modelling, and personalized medicine. We present CFB-GBM v2.0, an extension of our previously released CFB-GBM dataset comprising 264 GBM patients treated according to the standard Stupp protocol. The primary contribution of this release is the completion of Gross Tumour Volume (GTV) delineations across all available timepoints ($t_0$, $t_1$ and $t_2$), increasing the overall GTV completion rate from 35% to 97%. This was achieved using a nnU-Net model pre-trained on BraTS 2021 and fine-tuned on CFB-GBM ground-truth contours, with the generated segmentations validated by five radiation oncologists. From these longitudinal GTV annotations, volumetric RANO 2.0 response category labels were derived for all available temporality pairs ($t_0 \rightarrow t_1$, $t_0 \rightarrow t_2$ and $t_1 \rightarrow t_2$). To further ease dataset usability and reproducibility, brain masks computed with HD-BET and pre-computed radiomic features extracted with PyRadiomics are provided for each patient timepoint and MRI modality. Additionally, the WHO classification guideline (2016 vs. 2021) applicable to each patient's diagnosis is now explicitly documented. CFB-GBM v2.0 is publicly available on The Cancer Imaging Archive (TCIA) at https://www.cancerimagingarchive.net/collection/cfb-gbm .
Mohammad Javad Ahmadi, Hamid D. Taghiradcs.RO cs.AI cs.LG
Automated training of surgeons is one of the most crucial factors that significantly minimize surgical training risks and expenses. With recent advances in artificial intelligence (AI) knowledge and available data from various surgeries, AI's involvement in surgical training is becoming very promising. It is recommended that at the early stages of AI development, it interferes in the surgery as a third agent alongside the trainer. As trust in AI increases, this process will lead to an AI agent acting as a trainer in the future. The first phase in which AI can intervene in the training process is to suggest an improved surgical path to the trainer. A platform must be constructed in the first step, to accomplish this task and to enhance the movement path of trainee surgeons. This paper introduces this platform along with an annotated capsulorhexis surgery dataset called the ARAS-Farabi dataset. In this research, a deep convolutional neural network is pre-trained with JIGSAWS and ARAS-Farabi surgical datasets that can extract surgical skill characteristics from surgery tool tip motion data. The proposed platform develops a reference model from the feature space of an expert surgeon's movement trajectory and proposes an improved path to enhance the skill of a novice surgeon. An optimization with two loss functions is utilized to create a path that raises the skill level of the novice surgeon's path while simultaneously predicting and preserving his/her intent. The results of this study reveal that, with the assistance of an AI agent, the trainee surgeon's movement path can be enhanced by at least 20 percent while maintaining his intentional objective. In addition to the recommended deep network, various tangible indicators have also been developed in this research to verify the level of trainee improvement.
Diffusion models have been widely explored in protein backbone generation due to their powerful generation capabilities.However, in today's AI-driven biological research, predicting the structure of unknown multi-chain protein aggregates (called "complexes" in biology) remains an unsolved challenge.This is because existing static or dynamic protein datasets focus solely on static snapshots or single-entity trajectories, neglecting the dynamic process of multiple monomers forming complexes.To alleviate this dilemma, we present DynaPPI, a dynamic protein dataset comprising molecular dynamics (MD) trajectories of protein complex formation from dissociated chains to the bound state, as a pivotal resource to bridge the gap between static structural biology and the inherently temporal nature of dynamic molecular interactions.Benefiting from this dataset, diffusion models can explicitly learn the dynamic binding trajectories of known complexes and accurately predict the structures of unknown complexes based on their diverse generative properties, thereby further catalyzing AI-driven structural biology and protein interactomics.
Medical visual grounding connects free-form clinical queries to spatial evidence in medical images and is an important component of interpretable medical artificial intelligence. However, general-purpose grounding models are predominantly trained on natural images, while existing medical localization resources remain fragmented across imaging modalities, datasets, and task formulations. To address this gap, we construct LocAnyMed-200K, a multimodal medical visual grounding dataset containing approximately 200K image-query-answer examples across computed tomography, optical medical imaging, ultrasound, and X-ray. We harmonize heterogeneous detection and localization resources into a unified free-form instruction format that supports one or multiple bounding boxes, point coordinates, and no-target outputs for negative queries. Full-parameter fine-tuning of LocateAnything-3B on LocAnyMed-200K improves F1@IoU 0.50 from 10.64 to 85.59 on a held-out evaluation split, demonstrating that large-scale domain-specific supervision can equip a general grounding model with effective medical localization capabilities. Beyond spatial coordinates, a clinically interpretable grounding system should also communicate the evidence supporting its prediction. We therefore derive LocAnyMed-CoT-20K, a rationale-augmented subset that connects anatomical context, visual observations, and spatial conclusions through structured reasoning and further improves cross-source generalization through fine-tuning. Together, these resources provide a unified foundation for studying both localization accuracy and rationale quality across heterogeneous medical imaging modalities. The code is publicly available at https://github.com/MiliLab/LocAnyMed.
Reconstructing dynamic human faces from brain activity provides a powerful way to study how the mind perceives identity, expression, and facial motion. However, progress in fMRI-based face decoding has been limited by scarce controlled, high-resolution neural datasets and by methods that struggle to recover both identity-specific appearance and time-varying facial dynamics. We present fMRI-Face, the first fMRI dataset paired with controllable full-HD digital human facial videos rendered at 1920$\times$1080 resolution. During scanning, participants watched photorealistic, background-free facial videos with controlled identity, expression, and head pose, while fMRI activity was recorded. The resulting dataset contains 62,856 paired fMRI-video samples, providing a structured resource for studying dynamic face perception and reconstruction. Building on this dataset, we propose fMRI2Face, a geometry-guided neural video decoding framework for reconstructing facial videos from fMRI signals. fMRI2Face derives two complementary neural controls from brain activity: Brain-derived Appearance Context, which captures global identity-related visual attributes, and Morphable 3D Facial Control, which provides explicit geometry-aware guidance for pose, expression, and non-rigid facial dynamics. These controls are integrated through Neural-Controlled Video Diffusion with auxiliary latent completion, enabling high-fidelity facial video reconstruction directly from brain activity. Experiments show that fMRI2Face consistently improves reconstruction fidelity, identity preservation, facial geometry, and motion consistency over representative neural decoding baselines. Together, fMRI-Face and fMRI2Face establish a controlled platform for studying dynamic face perception and provide a new benchmark for fMRI-based digital human reconstruction.
Existing BraTS-GLI datasets provide a widely used benchmark for adult glioma MRI segmentation, but their task definition focuses on tumor subregions and does not systematically represent coexisting white matter hyperintensities (WMH). In joint segmentation settings, such unlabeled abnormalities introduce task-specific label noise by treating pathological regions as normal tissue. To address this limitation, we introduce BraTS-GLI Anatomy-Lesion, a controlled-access, labels-only derived resource built from the BraTS 2023-GLI training cohort. The resource provides 1,251 unified eight-class anatomy-lesion label sets aligned with the original four-modal MRI cases, including image-repair labels for 116 cases requiring repaired imaging inputs. The cohort is organized into a 394-case purified subset and an 857-case extended subset, with case-level metadata covering label source, image-repair requirements, quality-control status, access conditions, checksums, and release boundaries. Compared with the original BraTS-GLI annotations, the resource substantially expands foreground supervision by incorporating healthy brain tissues and previously unlabeled coexisting abnormalities within a unified label space. A validation study using MedNeXt and T1/FLAIR inputs suggests that WMH-aware supervision preserves healthy-tissue segmentation performance across both in-domain GLI and external WMH datasets, while improving sensitivity to coexisting lesions relative to noisy-control training. The resource is intended for scientific research and supports joint anatomy-lesion supervision, label-noise analysis, and reproducible evaluation. Data are available at https://www.synapse.org/Synapse:syn75210889/wiki/, and code is available at https://github.com/xyx200/brats-gli-anatomy-lesion-code. The data resource DOI is https://doi.org/10.7303/SYN75210889.
Katie I. Murray, Anna C. Bowland, Marina Ramon +9cs.CV
Leprosy (Mycobacterium leprae) has been confirmed in wild western chimpanzees (Pan troglodytes verus) in West Africa, presenting as clear and progressive visual symptoms. Manual review of camera-trap footage at landscape scale is infeasible, motivating the need for automated screening. We present the first deep learning pipeline for wildlife leprosy detection and contribute the PanLep300 dataset of 125,670 annotated bounding-box crops across 953 tracks from 303 camera-trap videos with ecologically-motivated splits that withhold whole individuals and camera installations. We benchmark spatial (2D), temporally aggregated (2.5D), and video-based (3D) classification approaches to investigate which approach is best suited to automated leprosy detection in wild apes. We find that simple aggregation of crop-level predictions consistently matches or outperforms both learned temporal models and end-to-end video architectures -- consistent with leprosy's static cutaneous presentation. We further find that performance is suppressed when tracklets contain frames of partially visible individuals -- as commonly occurs at the start and end of a track -- and demonstrate that this can be addressed through targeted construction and aggregation strategies.
Ethan B. Trepka, Ruobing Xia, Shude Zhu +6q-bio.NC cs.CV
The primate visual system is typically divided into two streams - the ventral stream, responsible for object recognition, and the dorsal stream, responsible for encoding spatial relations and motion. Recent studies have shown that convolutional neural networks (CNNs) pretrained on object recognition tasks are remarkably effective at predicting neuronal responses in the ventral stream, shedding light on the neural mechanisms underlying object recognition. However, similar models of the dorsal stream remain underdeveloped due to the lack of large scale datasets encompassing dorsal stream areas. To address this gap, we present STSBench, a dataset of large-scale, single neuron recordings from over 2,000 neurons in the superior temporal sulcus (STS), a nearly 50-fold increase over existing dorsal stream datasets, collected while Rhesus macaques viewed thousands of unique, natural videos. We show that our dataset can be used for benchmarking encoding models of dorsal stream neuronal responses and reconstructing visual input from neural activity.
While Multimodal Large Language Models (MLLMs) have demonstrated remarkable success in 2D medical image understanding, their extension to 3D volumetric imaging remains hindered by prohibitive annotation costs and dataset opacity. Current data formats, predominantly consisting of rigid Visual Question Answering (VQA) pairs or unstructured final clinical reports, typically fail to capture explicit clinical reasoning. To address this limitation, we introduce a large-scale structured reasoning dataset constructed via a novel slice-wise data synthesis paradigm. Inspired by the genuine diagnostic workflow of radiologists, this paradigm models visual cognition by decomposing the complex 3D reading process, translating global clinical priors into fine-grained, per-slice observations that are subsequently synthesized into an interpretable Chain-of-Thought (CoT). Crucially, this synthesized reasoning framework enforces essential clinical principles: sequential spatial tracking, multi-slice spatial awareness for artifact mitigation, and differential exclusion. To validate this approach, we instruction-tune a standard 2D-pretrained MLLM baseline using the synthesized data to enhance its volumetric comprehension. Comprehensive evaluations across multiple 3D medical benchmarks demonstrate that our method yields significant performance improvements over the 2D baseline. Furthermore, the resulting model exhibits robust spatial reasoning capabilities and rivals resource-intensive native 3D architectures, effectively bridging the performance gap. Ultimately, this data-centric strategy unlocks deep volumetric understanding and highly interpretable clinical logic without requiring computationally expensive 3D-specific pre-training. The complete repository, including datasets and training workflows, is publicly available at https://github.com/2020420145009/hounsfield.
Elham Amjadi, Amin Bahreini, Sayed Mohammad Hasan Emami +4cs.CV
Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related deaths globally, with approximately 1,926,425 new cases and 904,019 deaths reported in 2022. Accurate histologic grading plays a critical role in prognosis and treatment planning for colorectal adenocarcinoma. In recent years, artificial intelligence and its subcategories, including machine learning and deep learning, have been increasingly employed for automated cancer detection and classification. An appropriate and well-organized dataset is the essential first step to achieve this goal. This paper introduces CRC-HGD, a histopathological microscopy image dataset of 1,914 images obtained from 214 colorectal adenocarcinoma patients (Grade I: 106, Grade II: 75, Grade III: 33). The specimens are H&E-stained colorectal tissue sections acquired at the Poursina Hakim Research Center of Isfahan University of Medical Sciences, Iran, diagnosed between 2014 and 2019, and graded according to the World Health Organization (WHO) criteria into three grades: well-differentiated (Grade I), moderately differentiated (Grade II), and poorly differentiated (Grade III). For each specimen, four magnification levels are provided: 4x, 10x, 20x, and 40x. The dataset is accessible via Mendeley Data (https://doi.org/10.17632/yfp5sfj47m.4) and at http://databiox.com, where the latest version is also available. The distinctive feature of this dataset is the provision of labeled specimens across all three differentiation grades at multiple magnification levels, enabling comprehensive computational analysis of colorectal cancer grading.
Uterine diseases represent an important category of gynecologic pathology and require accurate histopathological assessment for diagnosis and treatment planning. Whole-slide images (WSI) have enabled the digital transformation of pathology workflows and provided new opportunities for artificial intelligence (AI) in computational pathology. In particular, multimodal models that jointly analyze histopathology images and pathology reports have shown promising potential for automated pathology report generation and AI-assisted diagnosis. However, the development of such systems remains limited by the scarcity of datasets that pair whole-slide images with clinically meaningful pathology reports. Instead, existing pathology datasets focus on patch- or slide-level annotations of a single endpoint (e.g., disease class), which do not fully capture the rich information in full clinical diagnostic workflow reports. Here, we introduce TUM-Uteria, a uterine pathology dataset comprising WSIs paired with diagnostic pathology reports at both the case and slide levels, collected from a tertiary medical center. The dataset contains 216 clinical cases, comprising 455 slide-level WSI-report pairs. The dataset underwent a structured multi-stage validation procedure involving board-certified pathologists to ensure reliable annotations. TUM-Uteria supports research in computational pathology, including whole-slide image analysis, multimodal learning, and automated pathology report generation.
Fernando López, Fernando Ibañez, Ana Martínez +4cs.CL cs.SD
Automatic speech recognition (ASR) has advanced remarkably for standard speech, yet speech affected by neurological conditions remains a challenge. We present S-DiverSe (Spanish Diverse Speech), a corpus of 3.2 hours of in-the-wild Spanish speech from 22 speakers with amyotrophic lateral sclerosis, Parkinson's disease, and stroke. The dataset contains 444 manually transcribed audio segments with metadata on speaker sex, disease type, and intelligibility. S-DiverSe is designed to support ASR evaluation and development for neurologically affected Spanish speech. We describe the dataset, analyze its composition, and report baseline ASR results alongside initial adaptation experiments. Our findings reveal that heuristic text post-processing is more robust than fine-tuning for out-of-domain neurological Spanish speech. This underscores the need for dedicated in-the-wild Spanish benchmarks.
Large vision-language models (LVLMs) have achieved strong performance across many medical imaging tasks, yet their application to ultrasound remains limited due to its inherent complexity and variability. In this work, we revisit what is truly needed to enable real-world ultrasound understanding. Instead of introducing complex architectures or elaborate training strategies, we show that data scale and clinically faithful data alignment are the key factors. We construct a large-scale dataset of 1.5M real-world ultrasound examinations, containing 17.7M images, multi-organ coverage, and paired uncurated clinical reports. Crucially, we organize the data at the examination level, aligning multiple images with their corresponding reports to reflect real clinical workflows. We then fine-tune a standard LVLM using low-rank adaptation (LoRA) on this dataset without task-specific modifications. Surprisingly, this simple recipe already leads to strong performance across diverse ultrasound understanding tasks, outperforming prior methods designed with more complex pipelines. Beyond these results, we present model and data scaling analyses that provide insights into the role of scale in ultrasound LVLMs.
Traditional Chinese Medicine (TCM) diagnosis, particularly through tongue inspection, faces persistent challenges in subjectivity and reproducibility. The application of multimodal artificial intelligence to TCM clinical tasks, such as syndrome differentiation and prescription generation, is significantly hampered by the semantic gap between visual tongue features and textual reasoning, as well as the lack of large-scale, standardized datasets. To address these challenges, we introduce MMIR-TCM, a novel framework that emulates the diagnostic process of TCM experts by integrating multimodal large language model(MLLM) with memory-augmented segmentation and retrieval-augmented generation (RAG). Employing a three-stage architecture, MMIR-TCM integrates a training-free Memory-SAM module for robust tongue extraction, a fine-tuned Qwen3-VL model for structured tongue diagnosis generation, and a Qwen3-based RAG component for evidence-grounded clinical decision support generation. The framework was developed and validated using MedTCM, a new large-scale multimodal dataset that we introduce specifically for advanced TCM research. To properly evaluate our framework's clinical accuracy, which existing metrics fail to capture, we also developed TDEU, a domain-specific evaluation metric incorporating semantic understanding and diagnostic importance. Our comprehensive experiments demonstrate that MMIR-TCM significantly outperforms leading models, including GPT-4o and Gemini 2.5 Flash.
Lucile Riaboff, Ny Aina Andriamampandry, Jean-François Bompa +14cs.HC cs.LG
Monitoring livestock behaviour under extensive conditions would provide valuable insights to assess animal adaption to environmental perturbations in agroecological systems (e.g., heat waves, parasitism, predator attacks). Animal behaviour can be monitored using accelerometer data collected from neck-collars combined with artificial intelligence models. However, large amounts of accelerometer data aligned with annotated behaviours are necessary to develop accurate models of behaviour prediction. In particular, developing reliable models for extensive systems requires data collected across a wide range of representative conditions. The dataset includes 79 hours of tri-axial accelerometer data aligned with behaviours manually annotated from video recordings for 120 Romane ewes born between 2021 and 2024. The ewes were derived from two divergent genetic lines after three and four generations of selection started 10 years ago: low and high social attractiveness, noted S-and S+, and low and high tolerance towards humans, noted H-and H+. They were reared under the extensive system applied to the Experimental Unit of La Fage (UEF, INRAE, Saint-Jean-et-saint Paul, Aveyron) where 250 sheep were reared exclusively outdoors on 280 hectares of rangeland in southern France. First batch of data was collected on March, June and July 2024 at the UEF under a range of extensive conditions, including sloping pastures and heat-wave periods. Ewes were equipped with accelerometer neck-collars specifically designed for young sheep on pasture. They were grouped on experimental paddocks for 4 to 8 hours and provided with fresh grass and ad libitum access to water. The animals were simultaneously video-recorded using an elevated CCTV camera. Behaviour annotation was carried out using Behavioral Observation Research Interactive Software focusing on the main behaviours on pasture: Grazing, Ruminating, Resting, Moving, and ''Other'', grouping all remaining activities. Annotations and corresponding accelerometer sequences were aligned using Python language, based on a time synchronization procedure. A second batch of data was acquired on November 2025 to supplement the dataset with the moving activity. For that purpose, ewes were equipped with the accelerometer collars and moved on tracks from the housing area to the pastures, corresponding to an approximately 10 minute-walk. The start and end times of the moves for each ewe were used to align the corresponding accelerometer data with the moving activity. These data were then merged with the dataset from the first batch. The resulting dataset is ready to use for applying artificial intelligence models to classify the 5 main behaviours of sheep under extensive grazing systems from accelerometer data.
We present a multi center breast fine needle aspiration cytology (FNAC) dataset designed for patch wise classification using C1 to C5 reporting labels. The prospective dataset includes 321 patients and 470 whole-slide images (WSIs) collected from participating tertiary medical centers in India between May 2023 and March 2026. Slides were stained using Papanicolaou (190 WSIs) or MayGrunwald Giemsa (280 WSIs), scanned on a Hamamatsu NanoZoomer S360 at 40X magnification and 0.25 microns per pixel, and stored directly in NDPI format. Across the 470 WSIs, 446 WSIs contain annotated patch regions, yielding 7,398 PNG image patches with expert-verified C1 to C5 labels. The release includes NDPI WSIs, WSI-level GeoJSON annotation files, extracted patch images, deidentified metadata, a data dictionary, a validation summary, a manifest linking WSIs to Zenodo records, and code for dataset inspection and reuse. The complete dataset is approximately 950 GB and is available through Zenodo.
Narayan Schuetz, Yuze Bai, Lianggang Pan +16cs.LG cs.AI
Mobile and wearable devices offer an unprecedented opportunity for continuous, passive health monitoring and active health coaching. However, the largest wearable datasets are not publicly available for research, and leading wearable foundation models trained on such datasets are rarely open-weight or come with reproducible training code. To accelerate open science in wearable health, we release OpenMyHeartCounts (OpenMHC), the largest and most comprehensive broadly accessible wearable health dataset to date, released to qualified researchers, alongside open-source implementations of recent wearable foundation models. OpenMHC, derived from over a decade of data collected through the My Heart Counts study app, includes >60 million hours of wearable data across 19 sensor channels (e.g., step count, heart rate, sleep, workouts) and up to 169 linked variables, including health, lifestyle, mood, and behavior from 11,894 consenting participants. Furthermore, we introduce a unified, open benchmark that enables standardized comparison of wearable health models across three tracks: health and behavior downstream prediction, multivariate data imputation, and time-series forecasting. We benchmark classical methods alongside recent wearable and multivariate time series foundation models. By releasing data under broad research access, alongside open-source code and model weights, at this unprecedented scale, we aim to democratize wearable health AI research and enable the community to drive open progress in this domain.
Cognitive workload monitoring is important for adaptive rehabilitation and assistive interfaces, where task difficulty, pacing, and feedback should be adjusted according to the user's cognitive state to avoid overload and under-challenge. Emerging extended reality and robot-assisted rehabilitation environments provide controllable training tasks, but they require unobtrusive sensing methods that can capture rapid ocular dynamics during interaction. Existing eye-movement-based cognitive workload recognition methods mainly rely on frame-based eye trackers, which often suffer from limited temporal resolution and degraded robustness under rapid eye movements. In contrast, event cameras provide microsecond-level temporal resolution, high dynamic range and low latency, making them suitable for capturing fine-grained ocular dynamics. Many previous studies rely on free-viewing or similar paradigms, where gaze locations can vary across tasks. As a result, models may learn associations between gaze-location distributions and cognitive workload, rather than workload-related eye movement characteristics themselves. In this work, we introduce EveLoad, which, to the best of our knowledge, is the first event-based eye-movement dataset with graded cognitive workload annotations, collected from 20 healthy participants under spatially constrained and task-driven conditions using a controlled N-back-guided fixation paradigm. Based on this dataset, we establish a benchmark for cognitive workload recognition with six workload levels and propose a learning framework that encodes spatiotemporal event representations. Experimental results show that our approach achieves an average subject-specific accuracy of 96.36% and 96.13% under mixed random split evaluation. These results suggest that event-based eye movements may provide a useful sensing pathway for future workload-aware rehabilitation.
Sudhanshu Mishra, Jialang Xu, Jensen Ang +3cs.CV cs.AI
Intraoperative Adverse Events (IAEs) detection is critical for improving surgical safety, with bleeding being among the most frequent events across many surgery types. Existing methods struggle to distinguish bleeding IAE from visually similar residual blood due to limited temporal reasoning. Moreover, modeling long surgical videos while preserving fine-grained temporal dynamics remains computationally challenging. We propose DBT-Bleed, a dual-branch multi-scale temporal modeling framework disentangling bleeding and normal representations using layer-wise temporal adapters for short- and long-term bleeding progression. To efficiently process long surgical videos without sacrificing fine-grained temporal information, we introduce HiRED, a Hierarchical Entropy-Driven frame selection strategy that retains temporally informative segments while removing redundancy. Experiments on the MultiBypass dataset demonstrate gains of 6.53% in F1, 5.62% in Recall and 9% in MCC values for bleeding IAE detection, consistently outperforming video-level baselines. Additionally, we evaluate cross-procedure generalization on a newly curated dataset from a different surgical procedure type, where DBT-Bleed demonstrates robust transferability by achieving gain of 6% in F1 and 8% in MCC under zero-shot setting. To support this evaluation, we introduce EndoPit-IAE, an Endonasal Pituitary Surgery dataset annotated for IAEs, representing the first IAE-annotated dataset in neurosurgery. Code will be made publicly available upon acceptance.
Niyoj Oli, Sachin Acharya, Sandesh Pokhrel +7cs.CV cs.AI
Gastrointestinal cancers represent a growing health burden in the South Asian region, driven largely by rapid changes in socio-economic conditions and lifestyle habits. However, early diagnosis remains limited by inadequate equipment, financial resources, and scarce GI expertise. AI-assisted diagnosis and report generation show great promise in alleviating this problem by providing non-specialist healthcare workers the technical expertise to perform diagnosis. Yet, almost all open-source, publicly available datasets are predominantly collected from the European region, with minimal representation from the South Asian region. The lack of open-source GI datasets from diverse geographic regions has made it difficult to assess whether population bias is present in existing models, and to develop geographically inclusive AI tools for automated GI diagnosis. To address this gap, we introduce SAGE: An Expert-Annotated South Asian GI Endoscopy dataset for Multimodal Learning and Hallucination Analysis, for image captioning, multi-label classification, and VQA tasks. It consists of 1,300 images, their captions along with hallucination tag, 18 labels and 14,276 question-answer pairs making it well-suited for diverse range of tasks including classification, benchmarking, and fine-tuning LMMs. We further conducted benchmarking of task-specific models, like multi-class classifiers on the effect of population shift which reveals that such models suffers the most with an average F1 score drop of 54 points on South Asian dataset. Further, benchmarking of contemporary LMMs reveals a substantial drop in the average GREEN score for anatomical landmark detection (0.308) and abnormality detection (0.410). We open-source our dataset under the CC BY-SA 4.0 license, and we hope to encourage others to contribute toward more inclusive dataset representation and help counteract population bias in medical AI.
Ronald L. P. D. de Jong, Tim J. M. Jaspers, Raf A. H. Vervoort +9cs.CV
Accurate recognition of anatomical structures is essential for safe and effective minimally invasive surgery (MIS), yet it remains underexplored in surgical computer vision due to limited annotated data and methods tailored primarily to natural scenes. In this work, we present a combined dataset and model framework to advance anatomy-aware perception in MIS. First, we introduce ATLAS-120k, a large-scale clip-level semantic segmentation dataset comprising over 120,000 annotated frames from 100 surgical videos spanning 14 procedures and multiple modalities, including laparoscopic and robot-assisted surgery. The dataset captures substantial procedural variability and was created using a scalable annotation pipeline that integrates expert manual labeling, automated propagation, iterative refinement, and surgeon verification to ensure high-quality annotations. Second, we propose ATLAS (Anatomy Recognition with Context Learning using Foundation Representations), a video semantic segmentation model specifically designed for surgical anatomy recognition. Unlike conventional approaches that emphasize object tracking, ATLAS leverages foundation-model embeddings together with lightweight temporal reasoning to incorporate contextual cues such as procedure type, surgical phase, and short-term visual memory. This design enables temporally consistent and accurate predictions while maintaining real-time feasibility. Together, the dataset and model establish a practical foundation for robust surgical scene understanding and support the development of clinically applicable guidance systems for minimally invasive surgery. The models, dataset annotations and annotation platform are publicly available at: https://github.com/TimJaspers0801/ATLAS.
Chu-Hsuan Lin, Alberto Mario Ceballos-Arroyo, Jisoo Kim +4eess.IV cs.CV
In this work, we present SemanticVessel, a dataset for fine-grained brain vessel segmentation in computed tomography angiography scans. Based on the detailed contrast provided by dynamic 4D-CTA scans, we generate segmentation traces for arteries and veins. We then use intensity-guided region growing to obtain segmentations of the majority of vascular territories in the human brain, which are refined and annotated with 20 unique arterial classes by an expert radiologist. Unlike existing datasets, where minor arteries are discarded as background content, we merge these minor arteries into a generic arterial class. Due to the multiple-phase acquisition of dynamic 4D-CTA, labels for a single phase can be re-used for other phases in the same series, greatly increasing the size of our dataset with no additional annotation cost. The results show that models trained with the additional generic artery class produce better fine-grained segmentations across the board. We will make our code, annotation GUI, and model weights available to the scientific community. Code, weights, and data will be made available on https://github.com/alceballosa/robust-vessel-segmentation