For finite-dimensional linear inverse problems where the variables are Gaussian, it is well-known that the minimum-mean-square error estimator takes the form of a regularized least-squares data fit. In this chapter, we show that this equivalence extends to a much broader infinite-dimensional setting where generalized splines take the role of linear regressors and generalized Gaussian processes on a nuclear space $S$ are the counterpart of Gaussian random vectors. The scope of this extension is of the same nature as the switch from the classic notion of function to that of a distribution, also known as a "generalized function." Our formalism involves a whitening/regularization operator $L: S\to S'$ whose continuous extension induces a native Hilbert space $H\subset S'$ that plays a central role in our characterization. The presentation is self-contained for the most part and remarkably general and powerful. It allows for the recovery of all known instances of such equivalences; in particular, the methods involving innovations and reproducing-kernel Hilbert spaces developed by Kailath and his students, and the mathematical correspondence between fractional splines and Mandelbrot's fractional Brownian motion (fractals), with the former being the optimal estimators of the latter. It also covers general Bayesian methods for the resolution of infinite-dimensional inverse problems.
Temporal point processes (TPPs) have widespread applications across various domains. Compared to modeling the conditional intensity of a TPP, modeling its cumulative conditional intensity function (CCIF) improves computational efficiency and eliminates numerical approximation errors. However, current CCIF parameterizations uniformly rely on Monotone Neural Networks (MNNs), which we identify as suffering from three structural deadlocks--convexity restrictions, saturation limits, and violations of CCIF modeling requirements--that fundamentally restrict their representational capacity for complex temporal dynamics. To resolve these bottlenecks, this paper proposes a novel framework called Monotone Alternating Splines (MAS). By leveraging distinct interpolation and extrapolation components, MAS provides a flexible and efficient framework for modeling CCIFs. Theoretically, MAS's interpolation provides strong fitting accuracy, while its extrapolation supports robust generalization, reducing the irreducible approximation gaps of MNNs. Extensive experiments show that MAS achieves superior performance on both synthetic and real-world datasets.